MutS protein initiates mismatch repair with recognition of a non-Watson-Crick base-pair or base insertion/deletion site in DNA, and its interactions with DNA are modulated by ATPase activity. Here, we present a kinetic analysis of these interactions, including the effects of ATP binding and hydrolysis, reported directly from the mismatch site by 2-aminopurine fluorescence. When free of nucleoti...

background: adequate self-care in diabetes causes quality of life promotion and decreases the number of inpatient cases. the health locus of control theory is used to assess adherence to diabetes regimen in some studies in developed countries. the purpose of this study was to determine the status of diabetes locus of control in a sample of diabetic patients in iran and investigation of it's rel...

A new algorithm for evaluating metamer mismatch volumes is introduced. Unlike previous methods, the proposed method places no restrictions on the set of possible object reflectance spectra. Such restrictions lead to approximate solutions for the mismatch volume. The new method precisely characterizes the volume in all circumstances. Introduction Two objects (surface reflectances) of the same co...

A new algorithm for evaluating metamer mismatch volumes is introduced. Unlike previous methods, the proposed method places no restrictions on the set of possible object reflectance spectra. Such restrictions lead to approximate solutions for the mismatch volume. The new method precisely characterizes the volume in all circumstances. Introduction Two objects (surface reflectances) of the same co...

Mismatch negativity (MMN), in the deviant-minus-standard event-related potential (ERP) difference-waveform, may represent a working memory trace of the tone difference. Most but not all studies find MMN reduced in schizophrenic patients. This report investigates if differences may be attributable to experimental condition (diffuse vs. focused attention), component identification (N1like vs. N2-...

Hereditary Non-polyposis Colon Cancer Syndrome (HNPCC) is the most common cause of familial colorectal cancer. Molecular genetic studies of HNPCC have shown evidence of locus heterogeneity, and mutations in four genes (hMSH2, hMLH1, hPMS1, and hPMS2) which encode components of the mismatch enzyme repair system may cause HNPCC. To determine the extent and nature of locus heterogeneity in HNPCC, ...