Objective Adenoid cystic carcinoma (ACC) is a rare malignant tumor originating from the salivary glands. It’s rather bland histological appearance that masks its ultimate biological aggressiveness. Evaluation of cell cycle and mitoses have been useful in predicting malignancy in many tumors. Ki-67 antigen is a human nuclear antigen that presents during all active phases of cell cycle. The aim ...

objective: gliomas are the most common primary brain tumors, and have been ranked as the fourth leading cause of cancer death. tumor mesenchymal-like stem cells (tmscs) contribute to the aggressive behavior of glial tumors by providing a favorable microenvironment for the malignant cells. the aims of our study were to identify differential proteome of tmscs derived from low vs. high grade gliom...

Cataract is one of the leading causes of blindness worldwide. A computer-aided approach to assess nuclear cataract automatically and objectively is proposed in this paper. An enhanced Active Shape Model (ASM) is investigated to extract robust lens contour from slit-lamp images. The mean intensity in the lens area, the color information on the central posterior subcapsular reflex, and the profil...

BACKGROUND Cervical cancer remains a major health problem, especially in developing countries. Colposcopic examination is used to detect high-grade lesions in patients with a history of abnormal pap smears. New technologies are needed to improve the sensitivity and specificity of this technique. We propose to test the potential of fluorescence confocal microscopy to identify high-grade lesions....

Bachground and purpose: Different grading systems for renal cell carcinoma (RCC) were proposed to assess patients’ outcome. Interobserver variability interfere with the widespread acceptance. Study of the tumor proliferative activity could provide another parameter for predicting biologic aggression and subsequent prognosis. Patients and Methods: Twenty patients who underwent radical nephrectom...

BACKGROUND Nuclear unrest is a term applied to Wilms' tumors (WT) that show nuclear abnormalities close to anaplasia but without abnormal mitoses. p53 is claimed to be associated with anaplasia and poor prognosis. This study was undertaken to evaluate the clinical significance of nuclear unrest and p53 immunostaining in Wilms' tumor. MATERIAL AND METHODS This is a retrospective study of 63 pa...

In a previous study significant glare sensitivity (using Vistech MCT8000) was found only in patients with posterior subcapsular cataracts (PSC) beyond the very early (LOCS II grade 1) stage. The aim of the present study was to evaluate glare sensitivity in patients with early cataracts. The brightness acuity tester (BAT) was used with the Pelli-Robson chart on 50 patients with early cataracts (...

We investigated the expression of thioredoxin (Trx) and thioredoxin reductase (TrxR) in 89 non-small cell lung carcinomas. Additionally, immortalized human bronchial epithelial cells (BEAS 2B) and four human lung carcinoma cells lines (A549, SK-MES-1, CALU-6, and A427) were studied by Western blot and reverse transcription-PCR for the synthesis of Trx and TrxR protein and mRNA expression in vit...

background : st6gal1, cox-2 and hb-egf genes are involved in different tumors and their enhanced expressions often correlate with poor prognosis. in this study we assay the expressions of these genes by reverse transcriptase-pcr in 54 breast cancer samples. methods : tissue samples were either formalin-fixed for histopathological examination or frozen for reverse transcriptase-pcr. image progra...