نتایج جستجو برای: nitrosamine

تعداد نتایج: 956  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1992
A J Klein-Szanto T Iizasa S Momiki I Garcia-Palazzo J Caamano R Metcalf J Welsh C C Harris

Using a xenotransplantation system in which immortalized nontumorigenic human bronchial epithelial cells (BEAS-2B cells) are grown in deepithelialized rat tracheas that are subcutaneously transplanted into athymic nude mice, we exposed BEAS-2B cells either to cigarette smoke condensate or to the tobacco-specific N-nitrosamine 4-(methylnitrosamine)-1-(3-pyridyl)-1- butanone. After 6 mo the carci...

2017
Naomi Ishii Min Gi Masaki Fujioka Shotaro Yamano Mai Okumura Anna Kakehashi Hideki Wanibuchi

We have previously demonstrated that diphenylarsinic acid (DPAA) promotes liver carcinogenesis in rats in a medium-term liver carcinogenicity bioassay. However, the effects of DPAA on other organs have not been determined. In the present study, the effects of DPAA on carcinogenesis were investigated using a rat multiorgan carcinogenicity bioassay. A total of 60 six-week-old male F344 rats were ...

2006
Tomoyuki Shirai

The potential enhancing effects of the regeneration response of the urothelium following ulcération of the bladder mucosa on A/-butyl-/V-(4-hydroxybutyl)nitrosamine Carcinogenesis were examined in male Fischer rats. The carcinogen was adminis tered in the drinking water at a concentration of 0.05% for 2 weeks. Ulcérationwas performed by a freezing technique 24 hr before the administration or ...

Journal: :Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene) 1987

Journal: :Beiträge zur Tabakforschung / Contributions to Tobacco Research 1975

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