The nerve injury, whether it results in tissue loss or not, involves cutting off the nerve, making impossible for two portions to interact and, as a result, impairing functionality. Mesenchymal stem cells are one of best options cell therapy many diseases due their distinct functional properties, such potent differentiation capacity, immunomodulatory capacity and growth support. secretome gener...

Abstract Background Head and neck is a relatively common site of occurrence for the peripheral nerve sheath tumors, majority these tumors are seen involving neck, vagus nerve, cervical sympathetic chain. Schwannomas mobile tongue rarely encountered, especially in pediatric population Case presentation We present case recurrent schwannoma 13-year-old female successfully managed with transoral ex...

As a promising alternative to autologous nerve grafts, tissue-engineered nerve grafts have been extensively studied as a way to bridge peripheral nerve defects and guide nerve regeneration. The main difference between autogenous nerve grafts and tissue-engineered nerve grafts is the regenerative microenvironment formed by the grafts. If an appropriate regenerative microenvironment is provided, ...

Mast cells are present in human lung tissue, pulmonary epithelium, and free in the bronchial lumen. By virtue of their location and their possession of specific receptors for IgE and complement fragments, these cells are sentinel cells in host defense. The preformed granular mediators and newly generated lipid mediators liberated upon activation of mast cells by a variety of secretagogues suppl...

Periodontal disease is a pathological condition that involves inflammation of the tooth supporting structures. It occurs in response to the presence of bacterial plaque on the tooth structure. The host defense system, including innate and adaptive immunity, is responsible for combating the pathologic bacteria invading the periodontal tissue. Failure to eradicate the invading pathogens will resu...

PURPOSE To develop a method for generating high spatial resolution (10 µm) matrix-assisted laser desorption ionization (MALDI) images of lipids in rodent optic nerve tissue. METHODS Ice-embedded optic nerve tissue from rats and mice were cryosectioned across the coronal and sagittal axes of the nerve fiber. Sections were thaw mounted on gold-coated MALDI plates and were washed with ammonium a...