UNLABELLED INTRODUCTION Wegener's granulomatosis presenting as diffuse alveolar hemorrhage is uncommon. However, the recognition of multisystem disease involving joints, kidney, eye and lung is critical for diagnosing Wegener's vasculitis. This is not the first report of this kind in the literature. CASE PRESENTATION A 51-year-old Croatian woman presented to our Emergency Department with a...

Authors describe the case of a 60-year-old diabetic man who presented with jaundice, ascites and significant weight loss over a period of 2 months. Physical examination revealed firm hepatomegaly with ascites. On evaluation, nephropathy, axonal neuropathy, carpal tunnel syndrome and decompensated cryptogenic liver disease with portal hypertension were found fitting with the diagnosis of diabeti...

Sarcoidosis is an inflammatory multisystem disorder of unknown cause. Practically no organ is immune to sarcoidosis; most commonly, in up to 90% of patients, it affects the lungs. The nervous system is involved in 5-15% of patients. Neurosarcoidosis is a serious and commonly devastating complication of sarcoidosis. Clinical diagnosis of neurosarcoidosis depends on the finding of neurological di...

OBJECTIVES The purposes of this study were to compare the relative fit of two alternative factor models of allostatic load (AL) and physiological systems, and to test factor invariance across age and sex. METHODS Data were from the Midlife in the United States II Biomarker Project, a large (n = 1255) multisite study of adults aged 34 to 84 years (56.8% women). Specifically, 23 biomarkers were...

Non-alcoholic fatty liver disease (NAFLD) is a public health problem worldwide. This narrative Review provides an overview of the current literature to support notion that NAFLD multisystem disease. Convincing evidence shows strong association between and risk developing multiple extrahepatic complications such as type 2 diabetes, cardiovascular (ie, predominant cause mortality in people with N...

Abstract A concerning development during the coronavirus disease pandemic has been multisystem inflammatory syndrome in children. Reports of this condition East Asia have limited. In South Korea, 3 cases were reported to national surveillance system for All case-patients hospitalized and survived with no major sequelae.

There has been significant advancement in the understanding of genetics pulmonary hypertension (PH), particularly those with heritable or idiopathic arterial hypertension. In addition to genetic variants a primarily vascular disease phenotype, prevalence PH other syndromes is increasingly recognized. We will review current knowledge associated multisystem syndromes. high coexisting cardiac and ...

Pheochromocytoma multisystem crisis is a rare and life-threatening disease that is associated with numerous symptoms and which is also difficult to diagnose. We herein report an autopsy case of a 61-year-old man who died due to pheochromocytoma multisystem crisis. The patient complained of vomiting and breathlessness. Computed tomography showed a shadow-like region with a similar appearance to ...

Allergic granulomatous angiitis (Churg-Strauss syndrome) is a variant of systemic vasculitis characterized by pulmonary and systemic small vessel vasculitis, extra-vascular granulomas and eosinophilia. Clinical features include presence of asthma and/or allergic rhinitis with constitutional symptoms such as fever and weight loss. Multisystem involvement includes pulmonary infiltrations, m...

A multisystem inflammatory syndrome is a rare emerging entity, resembling Kawasaki disease after covid 2019 viral illness(1). Here, we describe case of MIS -A in 21year old girl who presented with fever, mucocutaneous rash and involvement, which was treated intravenous immunoglobulins methylprednisolone, resulting uneventful recovery prompt treatment care at Jaffna Teaching hospital.