The study describes chitosan membrane platform modified with nanostructure pattern which using nanotechnology to fabricate. The cell-substrate interaction between neuro-2a neuroblasts cell lines and chitosan membrane (flat, nanostructure and nanostructure pattern types) was investigated. The adhered morphology of neuro-2a cells depends on the topography of chitosan surface. We have found that n...

Chitosan is biocompatible polymer obtained from chitin, the building component of the crustacean shells. In this paper we make an attempt to review the current state of knowledge on some biological effects of chitosan in comparison with those of cationically modified chitosan, N-(2-hydroxypropyl)-3-trimethylammonium chitosan chloride (HTCC) that was recently synthetized by us by covalent attach...

Polymeric nanoparticles were developed from a series of chemical reactions using chitosan, polyethylene glycol, and a cell-targeting peptide (CP15). The nanoparticles were complexed with PLK1-siRNA. The optimal siRNA loading was achieved at an N : P ratio of 129.2 yielding a nanoparticle size of >200 nm. These nanoparticles were delivered intraperitoneally and tested for efficient delivery, cyt...

Induced biomineralization of materials has been employed as a strategy to increase integration with host tissue, and more recently as a method to control cell function in tissue engineering. However, mineralization is typically performed in the absence of cells, since hypertonic solutions that lack the nutrients and culture components required for the maintenance of cell viability are often use...

Optical properties of spin-cast chitosan films were determined in the vacuum ultraviolet (VUV) through visible regions of the spectrum using spectroscopic ellipsometry. The onset of absorption in the ultraviolet was determined for chitosan films modified with succinic anhydride (SA) and glycidyl phenyl ether (GPE). This absorption was accounted for by including Gaussian and Tauc– Lorentz shaped...

PURPOSE To quantify the internal free surface in various resin cements and glass-ionomer-based materials. MATERIALS AND METHODS Materials tested were Nexus fluid (NXF) and viscous (NXV), Vitremer (VTM), Fuji II LC (FII), Vitremer Luting Cement (VLC), Dyract (DYR) and Compoglass (COM). Samples (n=5) were made of each material between two microscopic glass slides under same weight. With a trans...

BACKGROUND The use of resin-modified glass Ionomer cement in sandwich technique is widely practiced with the advent of various newer generation of composites the bond between resin-modified glass Ionomer and these resins should be validated. This study is done to evaluate the interfacial microgaps between different types of liners and dentin, liners and composite (Filtek p60 [FLp60]) using scan...

BACKGROUND Glass ionomer cements are widely used in pediatric practice due to their advantage of fluoride release and chemical bond to tooth structure. Adherence of the restorative material to the cavity walls is one of the most important characteristic for it to be proven as an ideal material as it prevents microleakage. AIMS AND OBJECTIVES This study was aimed at evaluating the microleakage...

To increase thermal stability for high performance applications of epoxy resin system – Diglycidal Ether of bisphenol-A (DGEBA), the epoxy backbone is modified to incorporate aromatic and heterocyclic rings i.e. the oxazolidone ring. FTIR studies were conducted during the synthesis at various intervals. Appearance of peak at 1754 cm confirms the presence of oxazolidone ring and absence of peak ...

The aim of this study was to synthesis the conjugated chitosan by covalent attachment of thiol moieties to the cationic polymer, mediated by a carbodiimide to improve permeation properties of chitosan. Thioglycolic acid was covalently attached to chitosan by the formation of amide bonds between the primary amino groups of the polymer and the carboxylic acid groups of thioglycolic acid. Hence, t...