Hypocalcaemia is one of the commonest disorders of mineral metabolism seen in children and can be a consequence of several different aetiologies. These include a failure of secretion or action of parathyroid hormone, disorders of vitamin D metabolism and abnormal function of the calcium-sensing receptor. A practical approach to the investigation, diagnosis and subsequent management of hypocalca...

Subcutaneous calcifications can lead to complications, including pain, inflammation, ulceration and immobilization. Studies on the pathophysiology of mineral compositions and effective treatment modalities are limited. We therefore studied 14 patients with subcutaneous calcifications. Mineral material was collected and analysed by Fourier transform infrared spectrometry. Blood analyses were run...

UNLABELLED The aim of this study was to assess bone mineral density and vitamin D metabolism in patients on chronic anticonvulsant therapy. METHODS Sixty-nine men, outpatients on chronic anticonvulsant therapy, who had been treated for at least 5 years, were studied, comparing them to thirty healthy controls. Bone mineral density was measured as well as serum levels of calcium, ionized calciu...

ELISA in the Assessment of Bone Resorption in Healthy Girls, Maria Luisa Traba, Jesús A. Calero, Cioly MéndezDávila, Carmen Garcı́a-Moreno, and Concepción de la Piedra (Fundación Jiménez Dı́az, Biochemistry Laboratory, Bone and Mineral Metabolism Section, 28040 Madrid, Spain; * address correspondence to this author at: Fundación Jiménez Dı́az, Laboratorio de Bioquı́mica, Sección Metabolismo Mineral...

BACKGROUND Abnormal mineral metabolism is associated with increased cardiovascular morbidity and mortality. The exact pathogenesis linking mineral metabolism to cardiovascular risk is unknown. This study was undertaken to investigate the association between serum phosphate and/or Ca x PO(4) product with serum levels of soluble E-selectin (sE-selectin), soluble intercellular adhesion molecule-1 ...

Body weight is positively associated with bone mineral density but the relationship between obesity and bone mineral density is unclear. Leptin and adiponectin are potential independent contributors to bone mineral density. We assessed the correlations of body composition, leptin and adiponectin with bone mineral density, and whether leptin, adiponectin and body composition determine bone miner...

Secondary hyperparathyroidism (SHPT) is one of the most clinically significant complications chronic kidney disease (CKD) due to associated mineral, bone disorders, and metastatic calcification. The indicators mineral metabolism 635 patients with different CKD stages 50 persons control group were analyzed using a neural network algorithm mathematical technology BootStrаp, which allowed determin...