The aim of this work is to elaborate a fast and reliable capillary electrophoresis method, for the separation of 1,4-benzodiazepine (BZD) derivates and their degradation products in acidic medium and in UV light. Because BZDs are neutral, hydrophobic compounds, the most efficient method proved to be micellar elektrokinetic capillary chromatography (MECC). For the separation we used a sodium tet...

The ability to separate nitroaromatic and nitramine explosives in seawater sample matrices is demonstrated using both MEKC and CEC. While several capillary-based separations exist for explosives, none address direct sampling from seawater, a sample matrix of particular interest in the detection of undersea mines. Direct comparisons are made between MEKC and CEC in terms of sensitivity and separ...

In 2011, co-workers and colleagues, mostly from Berlin, and around the world, formulated the idea of establishing the “Roland Hetzer International Cardiothoracic and Vacsular Surgical Society (RHICS)”. Despite the fact that unlike in the United States or Japan scientific societies named after highly-recognized and respected individuals are uncommon in Europe, this idea quickly gained support fr...

A cyclodextrin-modified micellar capillary electrophoretic method (MECC) was developed using mixtures of beta, cyclodextrins (beta-CD) and mono-3-O-phenylcarbamoyl-beta-CD as chiral additives for the chiral separation of miconazole with the dual CDs systems. The enantiomers were resolved using a running buffer of 50 mmol/L borate pH 9.5 containing 15 mmol/L beta-CD and 15 mmol/L mono-3-O-phenyl...

A comparison of the use of aqueous and nonaqueous buffers in association with beta-CD for the chiral separation of (R)- and (S)-3,4-methylenedioxymethamphetamine and related compounds is described. The (R)- and (S)-isomers of 3,4-methylenedioxymethamphetamine (MDMA) and its major metabolite 3,4-methylenedioxyamphetamine (MDA) were prepared. Under aqueous and nonaqueous buffer conditions and bas...

INTRODUCTION Modern phytotherapy and quality assurance requires stability data on bioactive metabolites to identify and minimise decomposing factors during processing and storage. A compound's stability in a complex matrix can be different from the stability of the purified compound. OBJECTIVE To test the stability of iridoids and acteoside and quantify changes in colour and microbiological q...

Enzyme reactions are important not only in life processes but also for the commercial production of various chemicals and foods. Many enzyme reactions of practical interest involve water-insoluble substrates and/or products. To improve the efficiencies of such reactions, one can exploit the system of reverse micelles to immobilize the enzymes and serve as a microheterogeneous reaction medium. E...

Funding: Research for this article was supported in part by a grant from the Social Sciences and Humanities Research Council of Canada. The funder played no role in the decision to submit the article or in its preparation. Competing Interests: The author has declared that no competing interests exist. Citation: Sismondo S (2007) Ghost management: How much of the medical literature is shaped beh...

Derivatization is a frequently used sample preparation procedure applicable to the enhancement of analyte detection sensitivity. Amino acids mostly require derivatization prior to electrophoretic or chromatographic analysis, especially if spectrophotometric detection is used. This study presents an on-line preconcentration technique for derivatized amino acids. The sensitivity of the method was...

This paper provides a new approach to recover relative entropy measures of contemporaneous dependence from limited information by constructing the most entropic copula (MEC) and its canonical form, namely the most entropic canonical copula (MECC). The MECC can effectively be obtained by maximizing Shannon entropy to yield a proper copula such that known dependence structures of data (e.g., meas...