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BACKGROUND Phthalates, ubiquitous environmental pollutants that may disturb the endocrine system, are used primarily as plasticizers of polyvinyl chloride and as additives in consumer and personal care products. OBJECTIVES In this study, we examined the association between urinary concentrations of nine phthalate metabolites and breast cancer (BC) in Mexican women. METHODS We age-matched 23...

BACKGROUND Previous studies have shown that women have higher urinary concentrations of several phthalate metabolites than do men, possibly because of a higher use of personal care products. Few studies have evaluated the association between phthalate metabolites, diabetes, and diabetes-related risk factors among women. OBJECTIVE We explored the association between urinary phthalate metabolit...

BACKGROUND Brachydactyly type A2 (OMIM 112600) is characterised by hypoplasia/aplasia of the second middle phalanx of the index finger and sometimes the little finger. BDA2 was first described by Mohr and Wriedt in a large Danish/Norwegian kindred and mutations in BMPR1B were recently demonstrated in two affected families. METHODS We found and reviewed Mohr and Wriedt's original unpublished a...

Designer drugs of the amphetamine type (eg, MDMA, MDEA, MDA), of the new benzyl or phenyl piperazine type (eg, BZP, MDBP, mCPP, TFMPP, MeOPP), or of the pyrrolidinophenone type (eg, PPP, MOPPP, MDPPP, MPPP, MPHP) have gained popularity and notoriety as rave drugs. These drugs produce feelings of euphoria and energy and a desire to socialize. Although in the corresponding drug scene designer dru...

PURPOSE To analyse change in distance between the humeral head and the glenoid fossa during traction in the maximally loose-packed position (MLPP) and the maximally closed-packed position (MCPP) under standardized conditions. SUBJECTS Six healthy subjects (three male and three female) with a mean age of 40.5 years, volunteered to participate in this study. MATERIALS AND METHODS Subjects wer...

OBJECTIVES The aim of the present project was to assess population exposure to pesticides in the vicinity of pesticide dump sites and make a preliminary evaluation of the potential health hazards to humans. MATERIALS AND METHODS Of the 286 pesticide dump sites registered in Poland, 40 were selected as the largest source of ecological hazard. The application of the Hazard Ranking System made i...

This work presents a method of screening of alkanophenoxy carboxylic (2,4-D, 2,4,5-T, MCPA, MCPP) and phenolic (dinoterb, dinoseb, pentachlorophenol) herbicides in water. The successive steps of the method, i.e. liquid-liquid extraction with ethyl acetate and methyl-tert-butyl ether and solid phase extraction using C18-modified silica gel and styrenedivinylbenzene copolymer-packed cartridges as...

We report on the successful functionalization of cotton fabrics with a water-stable metal-organic framework (MOF), UiO-66, under mild solvothermal conditions (80 °C) and its ability to adsorb and degrade water micropollutants. The functionalized cotton samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), transmiss...

This is a comprehensive review of biological abnormalities observed in bipolar/unipolar mood disorders. We do not ignore that conflicting results may be found in the literature, but attempted, nevertheless, to summarize the currents trends. Hypotheses: decreased sensitivity of pituitary glucocorticoid receptors to dexamethasone and/or hyperresponsivity of the adrenal gland to ACTH stimulation a...