Cystatin C is a 13 KD basic protein that is a member of the cystatin superfamily
of cysteine protease inhibitors. The cystatin C gene seems to be a house
keeping gene, which is compatible with a stable production rate of cystatin C by
most cells. This protein is freely filtered through the glomerulus and almost completely
reabsorbed and catabolized by proximal tubular cells.
Because of the...