background: acute myeloid leukemia (aml) with translocation (3,3) is a form of aml that may present de novo or may arise from a previous myelodysplastic syndrome. it is often associated with normal or elevated peripheral blood platelet count and increased bone marrow megakaryocytes with associated multi lineage dysplasia. a subset of patients present with hepatosplenomegaly while a few cases ha...

introduction nausea and vomiting are the most common side effects of chemotherapy in the pediatrics with cancer which affect their quality of life. use of some methods of complementary medicine in leukemia patients is problematic. because, leukemia patients are at risk of infection and bleeding, therefore the use of acupressure, acupuncture, and deep massage can be risky in these patients. slow...

background human t-cell lymphotropic virus types ι and ιι (htlv-ι and htlv-ii) are deltaretroviruses which may cause leukemia, lymphoma and htlv-associated myelopathy/tropical spastic paraparesis (ham/tsp). in addition, htlv-1 may be related to thalassemia and hemophilia cases after blood transfusion. objectives the aim of this study was evaluation of the prevalence of htlvs in patients with he...

Abstract Mixed phenotype acute leukemia (MPAL) is an uncommon type of leukemia. It one kind malignant clonal diseases that expresses more than genealogical specific antigen simultaneously. Most MPAL patients are associated with chromosomal abnormalities and molecular genetic changes, such as t(9;22) (q34;q11) KMT2A (MLL) rearrangement. These usually have important guiding significance in diagno...

Background & Objective: Acute promyelocytic leukemia (APL) with t(15;17)(q22;q12) is a relatively common subtype of acute myeloid leukemia (AML).  Here, our objective was to ascertain the survival of patients with this leukemia in north-east of Iran. Methods: Survival rates of 42 APL patients with t(15;17)(q22;q12) were assessed. Clinical information was ...

background: serum lipids abnormalities have been observed in various forms of cancers including acute leukemia. investigators report decreased total cholesterol and hdl, and elevated triglyceride in leukemic patients. limited studies had been performed to discover the correlation between abnormal lipids profile and disease activity in leukemic patients in iran. this study was done to evaluate t...

background: global death toll of acute leukemia (al), as a heterogeneous group of hematopoietic malignancies, is rather high, i.e. almost 74% of 300,000 new cases die every year. this reflects a poor prognosis of this malignancy in most parts of the world, where contemporary and rather complex remedies are not available. there are a few well documented reports about the epidemiologic features o...

some of the genotypes of cytokines are associated with acute graft versus host disease after bone marrow transplantation. the purpose of the present investigation was to find out the possible association between transforming growth factor beta-1 (tgf-β1) codon 25 polymorphism (rs:1800471) and acute graft versus host disease (agvhd) after bone marrow transplantation from the sibling with the sim...

During aging phenotypic changes in the hematopoietic system occur, and possible reason of these can be accumulation gene mutations stem cells or early blood progenitors. Although are mostly neutral, some may give progenitor a proliferative advantage. In this case clonal hematopoiesis will arise, which is characterized by formation genetically distinct subpopulation cells. Clonal become basis fo...

Abstract Study question What is the current status of fertility preservation (FP) male cancer utilization, efficacy and safety in China what national trends could be observed? Summary answer In this report on FP over a 11-year period, data population trends, region development are analyzed. known already Cryopreservation sperm, standard option to preserve patient's fertility, very advantageous ...