نتایج جستجو برای: lassa fever
تعداد نتایج: 96729 فیلتر نتایج به سال:
INTRODUCTION: Lassa fever (LF) affects all body systems, however, inadequate knowledge exists on the involvement of pulmonary system in LF infections. This scoping review, therefore, aimed to describe LF. MATERIAL AND METHODS: We conducted an extensive search literature two databases, namely PubMed and Google Scholar. Overall, 5,217 articles were retrieved from a database search, out which 107 ...
BACKGROUND Lassa fever (LF), an often-fatal hemorrhagic disease caused by Lassa virus (LASV), is a major public health threat in West Africa. When the violent civil conflict in Sierra Leone (1991 to 2002) ended, an international consortium assisted in restoration of the LF program at Kenema Government Hospital (KGH) in an area with the world's highest incidence of the disease. METHODOLOGY/PRI...
Several arenaviruses endemic to South America (Junin, Machupo, and Guanarito) and Africa (Lassa) are known to cause frequently fatal haemorrhagic fever. With the exception of ribavirin, which has demonstrated efficacy in cases of Lassa fever, there is no other effective therapeutic for the treatment of arenaviral haemorrhagic fever. We have recently reported that consensus interferon-α (IFN alf...
We report a case of Lassa fever in a US traveler who visited rural Liberia, became ill while in country, sought medical care upon return to the United States, and subsequently had his illness laboratory confirmed. The patient recovered with supportive therapy. No secondary cases occurred.
Vito Martella, Alessandro Bianchi, Irene Bertoletti, Luca Pedrotti, Alessandro Gugiatti, Alessia Catella, Paolo Cordioli, Maria S. Lucente, Gabriella Elia, and Canio Buonavoglia Author affi liations: Università di Bari, Bari, Italy (V. Martella, M.S. Lucente, G. Elia, C. Buonavoglia); Istituto Zooprofi lattico Sperimentale della Lombardia e dell’Emilia Romagna, Sezione di Sondrio, Italy (A. Bia...
The patient was successfully extubated. He was transferred to a pneumology ward on day 9 and discharged on day 15. Antimicrobial treatment was stopped on day 10. Most nonhuman strains of V. metschnikovii are usually found in aquatic habitats (e.g., lakes and marine waters). Human clinical infections with this bacterium are rare; however, cases of epidemic diarrhea caused by V. metschnikovii hav...
Haemorrhagic fever viruses (HFVs) are a diverse group of viruses that cause a clinical disease associated with fever and bleeding disorder. HFVs that are associated with a potential biological threat are Ebola and Marburg viruses (Filoviridae), Lassa fever and New World arenaviruses (Machupo, Junin, Guanarito and Sabia viruses) (Arenaviridae), Rift Valley fever (Bunyaviridae) and yellow fever, ...
Lassa virus (LASV) is an arenavirus whose entry into host cells is mediated by a glycoprotein complex (GPC) comprised of a receptor binding subunit, GP1, a fusogenic transmembrane subunit, GP2, and a stable signal peptide. After receptor-mediated internalization, arenaviruses converge in the endocytic pathway, where they are thought to undergo low-pH-triggered, GPC-mediated fusion with a late e...
Five cases of Lassa fever have been imported from West Africa to the United States since 1969. We report symptoms of the patient with the second imported case and the symptoms and long-term follow-up on the patient with the third case. Vertigo in this patient has persisted for 30 years.
In the light of progress in virology, it comes as a surprise to discover a disease, an epidemic disease moreover, caused by a "new "virus. This has happened twice in recent years. The diseases, Marburg virus disease and Lassa fever, are caused by unrelated viruses that are highly pathogenic for man and both have been responsible for illness and death among laboratory scientists and medical pers...
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