Hemophagocytic lymphohistiocytosis (HLH) has a well known association with lymphomas, especially of T cell origin. Prognosis of lymphoma associated HLH is very poor, especially in T cell lymphomas; and, therefore, early diagnosis might alter the outcome. Though association of HLH with systemic anaplastic large cell lymphoma (ALCL) is known, its occurrence in primary cutaneous ALCL (C-ALCL) is d...

Anaplastic large cell lymphoma (ALCL) is a distinct subset of T-cell non-Hodgkin's lymphoma. As a consequence of its low incidence, general pathogenic consideration of ALCL is lacking. In this review, we summarize the pathogenesis, epidemiology, clinical manifestations, and treatment of ALCL, so as to better understand key stages of the development of this disease and provide valuable informati...

Background: Chronic lymphocytic leukemia (CLL) can transform into fast growing lymphoma for diffuse large B-cell lymphoma (DLBCL) called Richter's syndrome (RS), which is commonly related to an existence of large B-cells with equal or larger size than macrophage nuclei or more than twice those of normal lymphocyte. We conducted a systematic review of the existing literature to assess the clinic...

mantle cell lymphoma is an aggressive type of b-cell non-hodgkin's lymphoma that originates from small to medium sized lymphocytes located in the mantle zone of the lymph node. the gastrointestinal tract is the predominant site of extranodal involvement in the form of multiple lymphomatous polyposis. multiple lymphomatous polyposis due to mantle cell lymphoma presenting with intussusception is ...

Diffuse large B-cell lymphoma can selectively and predominantly infiltrate lymph node sinuses this pattern has been recognized as an unusual morphologic variant of entity. Sinusoidal lymphomas with CD30 expression are even more rare.We present a 63-year-old female, who came in chief complaint mass the axillar region for 2 months. The lymphnode ultrasound revealed multiple suspicious lymphadenop...

Non-Hodgkin lymphoma is very uncommon in infancy and skin as the primary site of involvement in Non-Hodgkin lymphoma is rarely encountered. We describe a 10-month-old infant with T-cell Non-Hodgkin lymphoma who presented with multiple skin nodules as the predominant feature of her disease. The clinical manifestations, treatment strategy and disease outcome are reviewed. Key words: Non-Hodgk...

Oral cavity T-cell lymphoma occurs rarely. This case report describes a patient with such a tumor. The case was a 75 years old man presented with a painless swelling on his hard palate mucosa. He had suffered from nose- bleeding and nasal obstruction. Pathology revealed the presence of a T-cell lymphoma tumor in the palate. Though rare, the signs and symptoms of the case suggest that T-cell lym...

background: burkitt’s lymphoma is a high grade b-cell neoplasm, which is a kind of small non-cleaved cell lymphoma . it is presumably the fastest growing human malignancy, and the patients are prone to develop tumor-lysis syndrome. here we present findings on our patients with burkitt lymphoma . materials and methods: this descriptive retrospective study included 46 children with abdominal burk...