نتایج جستجو برای: intensive insulin therapy
تعداد نتایج: 934970 فیلتر نتایج به سال:
Hypoglycemia is a common and serious problem among patients with diabetes mellitus. It is also perceived as the most important obstacle to tight glucose control using intensive insulin therapy in critically ill patients. Because glucose is an obligatory metabolic fuel for the brain, hypoglycemia always represents an emergency that signals the inability of the brain to meet its energy needs. Whe...
A 13-year-old girl with type one diabetes mellitus poorly controlled for seven years, presented with total body edema and rapid weight gain (7 kg in 10 days). The edema developed one week after the initiation of an intensive insulin treatment. Initially, it started as lower limb edema; other causes of edema were excluded. With current trends toward intensive insulin therapy, clinicians need to ...
BACKGROUND Since Van den Berghe et al published their study on tight glucose control in 2001, intensive insulin therapy (IIT) has been increasingly used for critically ill patients worldwide. However, recent studies reported a significantly increased risk of hypoglycemia without a significant reduction in mortality. OBJECTIVE The purpose of this article was to evaluate the effect of IIT with ...
BACKGROUND Hyperglycemia is common in critically ill hospitalized patients, and it is associated with adverse outcomes, including increased mortality. The objective of this meta-analysis was to determine the effect of insulin therapy initiated during hospitalization on mortality in adult patients with a critical illness. METHODS An electronic search in the English-language articles of MEDLINE...
In 2008, there were clinical trial advances in 3 areas that will impact on the way stroke care is practiced in the emergency department and intensive care unit (ICU). These include (1) the positive results of the European Cooperative Acute Stroke Study (ECASS) III trial, extending the time window for intravenous thrombolytic therapy for acute ischemic stroke; (2) the negative results of 2 trial...
abstract background: better control of blood sugar and reduction of diabetes complications through insulin therapy could convince people to choose this method. however, patients might refuse insulin therapy due to its painful injection, limitations in daily activities, and hypoglycemia. thus, insulin therapy could have both positive and negative effects on patients’ quality of life (qol). there...
BACKGROUND Type 2 diabetes poses an increasing healthcare burden in Japan. Although insulin treatment has diversified in recent years, the literature on the utilization of healthcare services among patients with type 2 diabetes undergoing different insulin therapy regimens is scarce. The current study aimed to characterize the real-world insulin treatment patterns and associated utilization of ...
A cute myocardial infarction (AMI) triggers an inflammatory reaction, which plays an important role in myocardial injury (1). Inflammatory markers such as C-reactive protein (CRP) reflect the extent of myocardial necrosis and correlate with cardiac outcomes following AMI (2–4). Hyperglycemia has proinflammatory effects, inducing the release of inflammatory cytokines (5) and is associated with i...
OBJECTIVES The goals of this study were to develop (1) a safe and effective protocol for the clinical control of type 1 diabetes using conventional self-monitoring blood glucose (SMBG) measurements and multiple daily injections with insulin analogues, and (2) an in silico simulation tool of type 1 diabetes to predict long-term glycemic control outcomes of clinical interventions. METHODS The v...
OBJECTIVE Protection of residual beta cell function at the time of diagnosis of insulin-dependent diabetes mellitus (IDDM) by intensive insulin therapy and the addition of nicotinamide (NA) has been established. The objective of this study was to evaluate the effect of a free oxygen radical scavenger such as vitamin E (Vit E) on residual beta cell function and parameters of metabolic control in...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید