Effects of cyclophosphamide (CY) on the antibody titer level and incidence and severity of swine serum (SS)-induced bile duct lesion (BDL) were examined. BDL induced by 0.2 ml of SS per head twice a week for 2 weeks was characterized by hyperplasia of biliary epithelial cells, proliferation of mucous glands, and periductal infiltration of eosinophils with mild fibrosis. CY showed no significant...

OBJECTIVES The beneficial effects of macrophage-targeted glucocerebrosidase (Ceredase) in patients with Gaucher disease are well established. A minority of recipients develop transient nonneutralizing antibodies to the exogenous enzyme. A 7-year-old patient with type 3 Gaucher disease whose clinical course began to deteriorate while receiving Ceredase developed a progressively increasing titer ...

background: the ability of polyclonal antibodies to react with many epitopes of an antigen makes them valuable reagents in research and diagnosis. the aim of this study was purification of mouse igg2a and production of polyclonal antibody against purified mouse igg2a subclass. materials and methods: mouse igg2a was purified by proa affinity. verification method of the purified antibody was sds-...

background: conventional hepatitis b virus (hbv) vaccination fails to achieve efficient protection in about 5–10% of the world population. hence, different strategies have been adopted to ameliorate hbv antibody titers. this study aimed to evaluate the concurrent application of tetanus‑diphtheria (td) and hbv vaccination on hepatitis b surface (hbs) antibody titer in low‑responder healthy indiv...

The effect on liver and heart allograft survival (ACI rats to Lewis rats) was studied after three methods of recipient presensitization and after different intervals between sensitization and transplantation. With comparable lymphocytotoxic antibody titers, liver allografts always survived longer than heart grafts. The titer, class and specificity of the antibodies varied with the method of sen...

BACKGROUND ABO-incompatible live donor liver transplant (ABOi-LDLT) is being widely done to bridge the gap of demand and supply of organs. Different desensitization regimes are being used to reduce titer of blood group antibodies for successful transplant and accommodation of graft. The authors used cascade plasmapheresis (CP) to bring down titer of naturally occurring blood group antibody to 1...

Background and Objectives: Chicken pox has potential complications during pregnancy for both the mother and her baby. The aim of this study was to determine the Varicella-zoster virus (VZV) immune status in pregnant women in Babol and its surrounding neighborhoods. Materials and Methods: This seroepidemiological study was carried out on 427 pregnant women referred to Rohani Hospital, Babol, no...