Octylphenol (OP) and Trichlorophenol (TCP) act as endocrine disruptors and have effects on male reproductive function. We studied the interactions between 4-tert-Octylphenol (4-t-OP), 4-n- Octylphenol (4-n-OP), 2,3,4-Trichlorophenol (2,3,4-TCP), 2,4,5-Trichlorophenol (2,4,5-TCP) urinary exposure levels and polymorphisms in selected xenobiotic metabolism enzyme genes among 589 idiopathic male in...

Background Infertility is a public health issue with significant impact on the well-being of affected couples. Aim This paper aims to detect determinants pregnancy and their outcome after assisted reproductive therapy (ART) in sample Palestinian society. Methods A retrospective observational study was carried out at Razan Medical Center for Infertility. Subjects were assigned into twelve catego...

Background: Although idiopathic azoospermia is a common reason for male infertility, the known etiological factors for this disease are remarkably very little. Recent evidences suggest that some occupational physical and chemical hazards could have negative effects on reproductive function and semen quality parameters of exposed workers. This study conducted to compare demographic characteristi...

Objective: Objective of this study was to explore the effect of empirical antibiotics and micro nutritional blends in infertile men having idiopathic oligospermia, asthenospermia and oligoasthenospermia Materials and Methods: This prospective cross sectional study was undertaken in a tertiary level infertility care unit of Dhaka between September 2005 and December 2007. Two hundred and seven ol...

The aim of this study was to evaluate the chromatin status in different groups of patients. Five groups of men were selected: pre-vasectomy; male factor infertility; varicocele; immunological male infertility; and idiopathic infertility. Chromatin status was evaluated using flow cytometry after staining the DNA with the fluorochrome propidium iodide. Differences were observed in the state of sp...

30% of infertile couples worldwide are diagnosed with unexplained or idiopathic infertility and the problem is defined as the lack of an obvious cause for a couple's infertility and the females' inability to get pregnant after at least 12 cycles of unprotected intercourse or after six cycles in women above 35 years of age for whom all the standard evaluations are normal. The veracity of 'unexpl...

Recent studies have shown significant associations of aberrant DNA methylation in spermatozoa with idiopathic male infertility, increased frequency of spontaneous abortions and imprinting disorders. Thus, the analysis of DNA methylation of specific genes in spermatozoa has the potential to become a new valuable diagnostic marker in clinical andrology. This perspective article discusses the curr...

OBJECTIVE To investigate the prevalence of positive serologic findings for celiac disease in Indian women with poor reproductive performance. DESIGN Cross-sectional except that the women with intrauterine growth restriction were followed prospectively until delivery. SETTING Department of Obstetrics and Gynecology of a tertiary teaching hospital, New Delhi. PATIENT(S) Eight hundred ninety...

Management of male infertility is always a difficult task, and the pathologic process is often poorly understood. Even though modern assisted reproduction techniques (ART) can help overcome severe male factor infertility, the application of these methods in all infertile couples would definitely represent over-treatment. Several conditions can interfere with spermatogenesis and reduce sperm qua...