Aggregating platelets release serotonin, which induces contraction of most vascular smooth muscle by activation of S2-serotoninergic receptors. Serotonin released in the circulation may contribute to the increase in peripheral resistance of hypertension as the responsiveness of blood vessels from hypertensive animals and humans to the vasoconstrictor action of the monoamine is augmented. The da...

BACKGROUND Although adiponectin levels have been reported to be correlated with albuminuria, this issue remains unresolved in non-diabetic hypertensive subjects, particularly when urinary adiponectin is considered. METHODS Urinary adiponectin levels were examined using an enzyme-linked immunosorbent assay in 229 participants. who used olmesartan as a hypertensive agent. Their albuminuria leve...

PURPOSE The purpose of this study was to diagnose hypertension- induced renal microvascular dysfunction using renal diffusion magnetic resonance imaging (MRI) and to identify any correlation between blood pressure level and apparent diffusion coefficient (ADC) values. MATERIALS AND METHODS The study included 77 consecutive patients (41 women and 36 men). The patients were divided into 4 group...

BACKGROUND In some hypertensive patients, psychological stress makes blood pressure difficult to control and causes physical symptoms such as headache or dizziness. We report the case of a hypertensive man whose psychological stress-induced increase in blood pressure was attenuated by cilnidipine. CASE PRESENTATION The patient (a 72-year-old man) had hypertension and was on antihypertensive t...

Hypertensive disorders of pregnancy (HDP) are rising in prevalence and associated with adverse maternal infant health outcomes. Current guidelines recommend labetalol, nifedipine, methyldopa as acceptable first-line agents to treat HDP outpatient settings. However, the current practice regarding antihypertensive medication usage selection remain unclear. A retrospective, observational cohort st...

BACKGROUND AND OBJECTIVE In this study, 123 recordings of blood pressure (BP) obtained by ambulatory BP monitoring were analyzed. These recordings were measured in 2011 in patients from a Spanish tertiary university hospital. All participating patients were treated with 2, 3 or 4 anti-hypertensive drugs. The main aim of this study was to determine differences in BP control, if any, depending on...

Hypertension is associated with low-grade inflammation, and Toll-like receptor 4 (TLR4) has been shown to be linked to the development and maintenance of hypertension. This study aimed to investigate the effects of scutellarin (administered by oral gavage daily for 2 weeks) on brain TLR4/nuclear factor kappa B-(NF- κ B-) mediated inflammation and blood pressure in renovascular hypertensive (usi...

Hypertension is a common comorbidity in obstructive sleep apnea/hypopnea syndrome (OSAHS). OSAHS can raise blood pressures to pre-hypertensive and hypertensive ranges, increase the prevalence of 'non-dipping' overnight pressure patterns, risk resistant hypertension.

background: resveratrol has beneficial effects on cardiovascular system. this study aimed at examining antidiabetic and antihypertensive effects of resveratrol in rats with simultaneous type 2 diabetes and renal hypertension. methods: eight groups (8-10 each) of male spargue-dawley rats, including a control, a diabetic (induced by streptozotocin and nicotinamide), a renal hypertensive (induced ...

in this paper, a formal model for antivirus update agent system is presented based on mobile agent technology and predicate/transition petri nets. the mobile agent system contains two mobile agents called dca and una. it sends out agents to update antivirus on client computers in a network. each agent takes on a specified responsibility. first, dca roams through the network and check the last d...