In this study, buccal mucoadhesive tablets of meloxicam were formulated for drug delivery as an alternative route. Direct compression method was applied for the preparation of tablets. Also, different polymers, including hydroxypropyl methyl cellulose (HPMC) 1000, 4000, and 10000, as well as carbopol 934p and carbopol 971p were used as the mucoadhesive polymer and retardant polymer. Thirteen fo...

The goal of this investigation was to determine the effectiveness hydrophilic polymers in preparing a solid dispersion enhance solubility and dissolution poorly water-soluble drugs, such as curcumin. In order prepare dispersion, curcumin uniformly distributed polymeric matrix polyethylene glycol (PEG 6000), hydroxypropyl methyl cellulose (HPMC E5), polyvinyl pyrrolidine (PVP K30), bovine serum ...

The aim of the present work was to prepare and evaluate sublingual fast dissolving films containing metoprolol tartrate-loaded niosomes. Niosomes were utilized to allow for prolonged release of the drug, whereas the films were used to increase the drug's bioavailability via the sublingual route. Niosomes were prepared using span 60 and cholesterol at different drug to surfactant ratios. The nio...

Fatty acid-free albumin has been the standard carrier for intravenous infusion of fatty acids to study in vivo lipid metabolism. However, subjects can have adverse reactions to infusion of albumin. We sought an alternative to albumin as a carrier for intravenous infusion of fatty acids, using the pig as a model. Cyclodextrins are naturally occurring water-soluble molecules that can serve as car...

The development of gluten-free bread production has drawn massive attention to decrease the number wheat imports in some developing countries and fulfilled needs people with celiac other diseases related gluten components. Since component flours taken a major role form an extensible structure dough, its removal emerged considerable issues production. Hydrocolloids are food additive which able g...