نتایج جستجو برای: human osteoblasts

تعداد نتایج: 1649555  

2006
Lucia Moldovan Wanda Buzgariu Oana Craciunescu Elena Iulia Oprita C. Dobos Otilia Zarnescu

The aim of our research was to obtain porous matrices from collagen and collagen-hyaluronic acid and to investigate their effect on two types of human cells: fibroblasts and osteoblasts. In order to fabricate the collagenous matrices, type I collagen solution and a mixture of type I collagen and hyaluronic acid solutions, in a weight ratio of 5:1 were conditioned as sponges by freeze-drying. ES...

Journal: :The Journal of biological chemistry 2005
Xiao-chun Bai Di Lu An-ling Liu Zhong-ming Zhang Xiu-mei Li Zhi-peng Zou Wei-sen Zeng Bao-luan Cheng Shen-qiu Luo

It has been established that reactive oxygen species (ROS) such as H2O2 or superoxide anion is involved in bone loss-related diseases by stimulating osteoclast differentiation and bone resorption and that receptor activator of NF-kappaB ligand (RANKL) is a critical osteoclastogenic factor expressed on stromal/osteoblastic cells. However, the roles of ROS in RANKL expression and signaling mechan...

Journal: :Journal of cell science 1992
M C Meikle S Bord R M Hembry J Compston P I Croucher J J Reynolds

Collagenase production by rodent osteoblasts in response to calciotropic hormones has led to the hypothesis that bone cells play a major role in bone resorption by degrading the surface osteoid layer, thereby exposing the underlying mineralized matrix to osteoclastic action. Many studies suggest, however, that this model might not apply to bone resorption in the human. Human osteoblasts have be...

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