نتایج جستجو برای: hna
تعداد نتایج: 247 فیلتر نتایج به سال:
Ischemia-reperfusion (IR) injury following lung transplantation remains a major source of early morbidity and mortality. Histologically, this inflammatory process is characterized by neutrophil infiltration and activation. We previously reported that lung IR injury was significantly attenuated in plasminogen activator inhibitor-1-deficient mice. In this study, we explored the potential role of ...
Sodium channel Na(V)1.7, encoded by the SCN9A gene, is preferentially expressed in nociceptive primary sensory neurons, where it amplifies small depolarizations. In studies on a family with inherited erythromelalgia associated with Na(V)1.7 gain-of-function mutation A863P, we identified a nonsynonymous single-nucleotide polymorphism within SCN9A in the affected proband and several unaffected fa...
Block of peripheral nerve sodium channels selectively inhibits features of neuropathic pain in rats.
Several sodium channel blockers are used clinically to treat neuropathic pain. However, many patients fail to achieve adequate pain relief from these highly brain-penetrant drugs because of dose-limiting central nervous system side effects. Here, we describe the functional properties of trans-N-{[2'-(aminosulfonyl)biphenyl-4-yl]methyl}-N-methyl-N'-[4-(trifluoromethoxy)benzyl]cyclopentane-1,2-di...
Trans-4-hydroxy-2-nonenal (HNE) is a potent cytotoxic and genotoxic compound originating from the peroxidation of n-6 polyunsaturated fatty acids. Its metabolism has been previously studied in the rat (Alary et al. 1995. Chem. Res. Toxicol., 8: 35-39). In addition to major urinary mercapturic derivatives, some polar urinary metabolites were isolated and could correspond to hydroxylated compound...
The effect of humic substances from different sources on the performance and selected biochemical indicators was studied in 150 one-day-old broiler chickens (Ross 308) divided into control (C) and two tested groups (n = 50). Chickens of tested groups were fed diets supplemented with natural humic compounds (group HS) and sodium humate (group HNa) at amounts of 5 g·kg-1 of feeds in phase 1 and 7...
در این پروژه یک روش سریع و حساس برای اندازه گیری مقادیر ناچیز آلومینیوم در نمونه های آب پیش بینی شده است. این فرایند تجزیه ای بر اساس تشکیل کمپلکس بین آلومینیوم(iii) و 3- هیدروکسی2- نفتالن کربوکسیلیک اسید(hna) است. شدت نشر فلوئورسانس سیستم در حضور آلومینیوم (iii)که منجر به تشکیل کمپلکس بین این یون و ترکیب مورد نظر می شود، بیشتر از سیستم فاقد آلومینیوم (iii) می باشد. شرایط بهینه در این پروژه م...
We report a simple and efficient silicon wet etchant HNA (Hydrofluoric acid, Nitric Acetic acid) for the stiction free release of nitride/metal micro/nanomechanical structures. The concentration was varied with aim developing slow etch rate, which could be utilized to suspend micron sub-micron cantilever fixed beam rate found decrease in HF increase HNO3 concentrations. Smooth surface high sele...
In this paper a popular time domain reduction method based on hankel norm approximation (HNA) is explored. This method suffers from a drawback of not matching steady state values for some of the systems. A very simple method is given to remove this drawback and an improvement is made so that the steady state value of the original model is also preserved in the reduced model. This increases sign...
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