نتایج جستجو برای: histiocytic lymphoma

تعداد نتایج: 103755  

Journal: :Hemato 2022

The definitions of follicular lymphoma (FL) and diffuse large B-cell (DLBCL) are evolving in the era personalized medicine. Early stages evolution FL have been recognized. Two histological manifestations early lesions situ neoplasia duodenal type FL. Additionally, frequently undergoes transformation, most common form being DLBCL. High-grade with double hit, translocations involving BCL2 MYC imp...

Journal: :Anales de la Real Academia Nacional de Medicina 2021

HLH is a specific disease and always syndrome characterized by excessive immune activation clinical analytical data of hyperinflammation that leads to short survival if the appropriate treatment delayed or not applied. It has been poorly diagnosed its incidence apparently increased in recent times, perhaps due greater recognition. Genetic /familial-based cases occur childhood from an inherited ...

2014
Raha A. Been Michael A. Linden Courtney J. Hager Krista J. DeCoursin Juan E. Abrahante Sean R. Landman Michael Steinbach Aaron L. Sarver David A. Largaespada Timothy K. Starr

Histiocytic sarcoma is a rare, aggressive neoplasm that responds poorly to therapy. Histiocytic sarcoma is thought to arise from macrophage precursor cells via genetic changes that are largely undefined. To improve our understanding of the etiology of histiocytic sarcoma we conducted a forward genetic screen in mice using the Sleeping Beauty transposon as a mutagen to identify genetic drivers o...

Journal: :Arquivos de neuro-psiquiatria 1990
J D Correale D A Monteverde J A Bueri E G Reich N Lucatelli

Nine-hundred-eighty-nine patients with lymphoma were studied. Fifty-three cases (5.3%) had lymphomatous craniocerebral infiltration. The principal factors of risk for this complication were: advanced stage of the lymphoma (III or IV), diffuse histiocytic, diffuse poorly differentiated lymphocytic, or mixed cellularity lymphoma histological type, bone marrow involvement, and previous systemic ch...

2016
Sarah C. Roode Daniel Rotroff Kristy L. Richards Peter Moore Alison Motsinger-Reif Yasuhiko Okamura Takuya Mizuno Hajime Tsujimoto Steven E. Suter Matthew Breen

BACKGROUND Leukemia/lymphoma cell lines have been critical in the investigation of the pathogenesis and therapy of hematological malignancies. While human LL cell lines have generally been found to recapitulate the primary tumors from which they were derived, appropriate characterization including cytogenetic and transcriptional assessment is crucial for assessing their clinical predictive valu...

Journal: :The New England journal of medicine 2008
G Lenz G Wright S S Dave W Xiao J Powell H Zhao W Xu B Tan N Goldschmidt J Iqbal J Vose M Bast K Fu D D Weisenburger T C Greiner J O Armitage A Kyle L May R D Gascoyne J M Connors G Troen H Holte S Kvaloy D Dierickx G Verhoef J Delabie E B Smeland P Jares A Martinez A Lopez-Guillermo E Montserrat E Campo R M Braziel T P Miller L M Rimsza J R Cook B Pohlman J Sweetenham R R Tubbs R I Fisher E Hartmann A Rosenwald G Ott H-K Muller-Hermelink D Wrench T A Lister E S Jaffe W H Wilson W C Chan L M Staudt

BACKGROUND The addition of rituximab to combination chemotherapy with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP), or R-CHOP, has significantly improved the survival of patients with diffuse large-B-cell lymphoma. Whether gene-expression signatures correlate with survival after treatment of diffuse large-B-cell lymphoma is unclear. METHODS We profiled gene expression in ...

Journal: :Blood 1976
P A Bunn P S Schein P M Banks V T DeVita

Fifteen of 52 patients (29%) with diffuse histiocytic and undifferentiated pleomorphic lymphoma developed central nervous system (CNS) complications, primarily leptomeningeal lymphoma. Lumbar puncture with cerebrospinal fluid cytology was the most useful test for diagnosis, and for following the response to therapy. Leptomeningitis developed during all stages of the patients' clinical course: a...

Journal: :Haematology and blood transfusion 1983
J Minowada K Minato E Tatsumi T Sugimoto S Nakazawa T Ohnuma I Kubonishi I Miyoshi A Frankel R C Gallo

The analysis of leukocyte differentiation has been greatly enhanced by developments in three areas of methodology: Firstly by the establishment of relatively stable permanent hematopoietic cell lines of a variety of origin, secondly by the development of numerous specific polyclonal and monoclonal heterologous antibodies to various leukocyte antigens, and thirdly by the introduction of many fun...

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