نتایج جستجو برای: hirudin variant 3

تعداد نتایج: 1893080  

"> In the present study the reaction kinetic and dynamic modeling of the reactor for syngas transformation into dimethyl ether u...

Journal: :The Biochemical journal 1994
J Y Chang

The folding of hirudin undergoes an initial stage of non-specific packing, followed by consolidation (re-organization) of partially packed intermediates to attain the native structure [Chatrenet and Chang (1993) J. Biol. Chem. 268, 20988-20996]. Non-specific packing leads to the formation of scrambled hirudins as folding intermediates. A systematic study was carried out to search for conditions...

2005
Beat J. Meyer Lina Badimon James H. Chesebro Juan J. Badimon

Background The major morbidity of percutaneous transluminal coronary angioplasty is acute thrombosis and restenosis of the dilated lesion. Platelet-thrombus deposition occurs within minutes after injury, is primarily mediated by thrombin, causes acute occlusion, and contributes to late restenosis. Experimentally, specific thrombin inhibitors have prevented mural thrombosis. However, local thera...

2006
Eva Bastida Antonio Ordinas Steven L Giardina G. A. Jamieson

Three different mechanisms have been detected for the aggregation of platelets by tumor cells in a homologous human system based on inhibition studies with apyrase, hirudin, and phospholipase D. In the major group, platelet aggregation induced by the SKBR3 (adenocarcinoma), SKNMC (neuroblas toma), HT29 (adenocarcinoma), and HT144 (melanoma) cell lines was inhibited by apyrase and phospholipase ...

Journal: :The Journal of Physiology 1927

J. Saien M. Kharazi S. Asadabadi

e"> The adsorption behavior of three amphiphilic ionic liquids (ILs), 1-alkyl-3- methylimidazolium chloride {[Cnmim][Cl], n=6<span style="font-family: SymbolMT; font-size: 10pt; color: #000000; font-styl...

Journal: :Molecules 2017
Edward Cedrone Barry W Neun Jamie Rodriguez Alison Vermilya Jeffrey D Clogston Scott E McNeil Yechezkel Barenholz Janos Szebeni Marina A Dobrovolskaia

The preclinical safety assessment of novel nanotechnology-based drug products frequently relies on in vitro assays, especially during the early stages of product development, due to the limited quantities of nanomaterials available for such studies. The majority of immunological tests require donor blood. To enable such tests one has to prevent the blood from coagulating, which is usually achie...

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