For the first time, a novel and efficient ionic liquid-based ultrasound-assisted in-situ solvent formation microextraction (IL-UA-ISFME) combined with high-performance liquid chromatography-ultraviolet detection (HPLC-UV) has been successfully developed for the determination of duloxetine (DLX) in human plasma. Herein, an environmentally-friendly hydrophobic ionic liquid (1-butyl-3-methylimidaz...

The development of high-performance liquid chromatography (HPLC) in the years of 1965 to 1985 was undeniably a success story. However, an important limitation of the technique remained: in comparison to capillary gas chromatography the resolving power accessible in a reasonable analysis time is poor. The introduction of a range of miniaturized liquid phase techniques, exploiting either pressure...

This article describes newly introduced high-performance liquid chromatography (HPLC), mass spectrometry (MS), data systems (CDS), and related products in 2022–2023. It summarizes their unique features significant user benefits, including relevant technical specifications.

This paper describes two rapid, sensitive and specific methods for the determination of fulvestrant in pharmaceutical preparations by high performance liquid chromatography (HPLC) and linear sweep voltammetry (LSV). HPLC method was used to study the degradation behaviour. Fulvestrant was subjected to degradation under the conditions of hydrolysis (acid and alkali), oxidation (30% H2O2). The lin...

t-2 toxin is the most poisonous trichothecene produced by fusarium species especially f.sporotrichioides . t-2 toxin is a biological contaminant in a number of agricultural commodities that can cause severe diseases among humans and animals and even lead to death. the aim of the current study is the analysis of t-2 mycotoxin in fusarium species by high-performance liquid chromatography (hplc) c...

the aim of the present investigation was to biotransform the anti-inflammatory compound meloxicam by enzymes present in whole cells of five actinomycete cultures to produce novel bioactive derivatives. among the actinomycetes screened, streptomyces griseus ncim 2622 was found to possess the enzyme system(s) that oxidize meloxicam into two metabolites whereas that present in s. griseus ncim 2623...

The anthocyanins of the fruit skin of Iranian forest pear (Sange Khouj) were separated, identified and quantified using high-performance liquid chromatography/diode array detection (HPLC/DAD) and HPLC/electrospray ionization /mass spectrometry (HPLC/ESI /MS). The individual anthocyanins were identified by comparing their mass spectral data and retention times with those of standards and publish...

Glyphosate is widely used in herbicides and is toxic to organism. Therefore accurate detection of glyphosate content is important for public health and food security. In this paper, methods such as gas chromatography (GC), high performance liquid chromatography (HPLC), gas chromatography-mass spectrometry (GC/MS), liquid chromatography-mass spectrometry (LC/MS), ion chromatography (IC), capilla...