My father in law, Cyril Daly, has died. He was a general practitioner in the north of Dublin. He was truly singlehanded—just him, no nurse, no secretary, no receptionist. Patients wanting to be seen simply turned up and waited during specified hours. The surgery, appended to the side of the house, had a waiting roomwith comfortable chairs and paintings to admire. No health promotion leaflets or...

I 33 SDS/PAGE has been used to study the proIntroduction The proteins in saliva are synthesized mainly in the acinar cells of the major salivary glands, namely the parotid, submandibular and sublingual. Minor components derived from serum are also present in the secretions of these three pairs of glands which, together with the secretions of the minor glands, gingival exudate, micro-organisms a...

Somehow, a quarter of a century has passed since the first issue of Pediatric Exercise Science went to print. This special issue celebrates these 25 years, the inspiration that led to the journal’s creation, the people who made it happen, the countless scientists who provided the substance, and, of course, the raison d’être of our field—the science of pediatric exercise. In the journal’s very f...

n engl j med 371;4 nejm.org july 24, 2014 369 care community in an ongoing national debate about our health care system, the likes of which had never occurred before. He continued writing about the health care system right up to the end of his life. Just months before he died, he wrote a compelling article for the New York Review of Books, entitled “On Breaking One’s Neck,” in which he reported...

There are four books describing early studies and views on light, optics and vision that are considered to be landmarks in this branch of science. The first of these is Euclid’s Optica, published about 300BC, in which he postulated that light travelled in straight lines; he described the laws of reflection and described them mathematically. The second is by Ptolemy. He is best known for his 15 ...

I t seems almost intuitive that developing a large and rich vocabulary is central to learning to read. Logically, children must know the words that make up written texts in order to understand them, especially as the vocabulary demands of content-related materials increase in the upper grades. Numerous studies have documented that the size of a person’s vocabulary is strongly related to how wel...

An interview with Charles Rosenberg conducted by Rafael Mantovani in November 2013 that addressed four topics. It first focused on the way in which Rosenberg perceived trends and directions in historical research on medicine in the United States during the second half of the twentieth century. The second focus was on his experience with other important historians who wrote about public health. ...

Pharmacy which is an art and science of preparing and dispensing drugs and Materia Medica gives the names, sources physical characters and chemical properties of herbs or substances used in medicine and their doses have been interwoven connected with medicine from the time immorial. This can be traced back to the findings of ancient Egyptian and Unani Physician like Hippocrates (460-377 B.C) Di...

Enhanced sensitivity to information of negative (compared to positive) valence has an adaptive value, for example, by expediting the correct choice of avoidance behavior. However, previous evidence for such enhanced sensitivity has been inconclusive. Here we report a clear advantage for negative over positive words in categorizing them as emotional. In 3 experiments, participants classified bri...