نتایج جستجو برای: growth enhancer
تعداد نتایج: 836026 فیلتر نتایج به سال:
In humans and mice, loss of HOXA13 function causes defects in the growth and patterning of the digits and interdigital tissues. Analysis of Hoxa13 expression reveals a pattern of localization overlapping with sites of reduced Bmp2 and Bmp7 expression in Hoxa13 mutant limbs. Biochemical analyses identified a novel series of Bmp2 and Bmp7 enhancer regions that directly interact with the HOXA13 DN...
Pyroligneous acid (PA) is often used in agriculture as a plant growth and yield enhancer. However, the influence of PA application on soil microorganisms not studied. Therefore, this study, we investigated effect (0.01–5% w/w soil) microbial diversity two different soils. At end eight weeks incubation, community dynamics were determined by Illumina-MiSeq sequencing 16S rRNA gene amplicons. The ...
Gammaretroviral and lentiviral vectors are promising tools for gene therapy, but they can be oncogenic. The development of safer vectors depends on a quantitative assay for insertional mutagenesis. Here we report a rapid, inexpensive, and reproducible assay which uses a murine cell line to measure the frequency of interleukin-3 (IL-3)-independent mutants. Lentiviral and gammaretroviral vectors ...
Rice Mutant Database (RMD, http://rmd.ncpgr.cn) is an archive for collecting, managing and searching information of the T-DNA insertion mutants generated by an enhancer trap system. We have generated approximately 129 000 rice mutant (enhancer trap) lines that are now being gathered in the database. Information collected in RMD includes mutant phenotypes, reporter-gene expression patterns, flan...
16 ROGERS, B. L., SOBNOSKY, M. G. & SAUNDERS, G. F. (1985). Transcriptional enhancer within the human placental lactogen and growth hormone multigene cluster. J . Biol. Chem. (in press). 17 PICARD, D. & SCHAFFNER, W. (1984). A lymphocyte-specific enhancer in the mouse immunoglobulin gene. Nature 307, 80-82. 18 EPHRUSSI, A., CHURCH, G. M., TONEGAWA, S. & GILBERT, W. (1985). Science 227, 134-140....
Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer
The evolution of prostate cancer from an androgen-dependent state to one that is androgen-independent marks its lethal progression. The androgen receptor (AR) is essential in both, though its function in androgen-independent cancers is poorly understood. We have defined the direct AR-dependent target genes in both androgen-dependent and -independent cancer cells by generating AR-dependent gene ...
A CREB-binding site as a target for decapentaplegic signalling during Drosophila endoderm induction.
Decapentaplegic (Dpp) is an extracellular signal of the transforming growth factor-beta family with multiple functions during Drosophila development. For example, it plays a key role in the embryo during endoderm induction. During this process, Dpp stimulates transcription of the homeotic genes Ultrabithorax in the visceral mesoderm and labial in the subjacent endoderm. Here, we show that a cAM...
Submit Manuscript | http://medcraveonline.com Abbreviations: PUFA: Polyunsaturated Fatty Acid; PCR: Polymerase Chain Reaction; DNA: Deoxyribonucleic Acid; RNA: Ribonucleic Acid; SFA: Saturated Fatty Acid; MUFA: Monounsaturated Fatty Acid; SCD: Δ9-desaturase; FASN: Fatty Acids Synthase; STAT5: Signal Transducer and Activator of Transcription 5; CEBPA: CCAAT/Enhancer-Binding protein (alpha); CLA:...
Enhancers could, in principle, function by increasing the rate of reinitiation on individual adjacent active promoters or by increasing the probability that an adjacent promoter is activated for transcription. We have addressed this issue for the repetitive metazoan rDNA enhancer by microinjecting Xenopus oocytes with enhancer-less and enhancer-bearing genes and determining by EM the frequency ...
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