نتایج جستجو برای: gcb pwm

تعداد نتایج: 4927  

2013
Caroline Bret Bernard Klein Jérôme Moreaux

Diffuse large B-cell lymphoma (DLBCL) is the most frequent type of non-Hodgkin lymphoma. DLBCL is a molecularly heterogeneous disease, and the addition of Rituximab to combination chemotherapy with cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP) has significantly improved the survival of patients. Gene expression profiling studies revealed that DLBCL comprises two main subgroup...

2018
Ying-Chang Li Yuan-Hsiao Chang Preetpal Singh Liann-Be Chang Der-Hwa Yeh Ting-Yu Chao Si-Yun Jian Yu-Chi Li Cher Ming Tan Chao-Sung Lai Lee Chow Shang-Ping Ying

The light emitting diode (LED) is widely used in modern solid-state lighting applications, and its output efficiency is closely related to the submounts' material properties. Most submounts used today, such as low-power printed circuit boards (PCBs) or high-power metal core printed circuit boards (MCPCBs), are not transparent and seriously decrease the output light extraction. To meet the requi...

2017
Zlata Novalić Sandra A W M Verkuijlen Mariska Verlaan Jos L H Eersels Inge de Greeuw Carla F M Molthoff Jaap M Middeldorp Astrid E Greijer

Undifferentiated nasopharyngeal carcinoma (NPC) is 100% associated with Epstein-Barr virus (EBV). Expression of viral proteins in the tumor cells is highly restricted. EBV reactivation by CytoLytic Virus Activation (CLVA) therapy triggers de novo expression of early viral kinases (PK and TK) and uses antiviral treatment to kill activated cells. The mechanism of tumor elimination by CLVA was ana...

Journal: :PLOS ONE 2021

Background SLFN11 has recently been reported to execute cancer cells harboring replicative stress induced by DNA damaging agents. However, the roles of under physiological conditions remain poorly understood. Germinal center B-cells (GCBs) undergo somatic hypermutations and class-switch recombination, which can cause genotoxic stress. Hence, we tested whether expression needs be suppressed in G...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2007
N Niitsu M Okamoto N Nakamura H Nakamine M Bessho M Hirano

BACKGROUND We studied the clinicopathological characteristics and prognoses of localized stage thyroid diffuse large B-cell lymphoma (DLBCL). PATIENTS AND METHODS This study included 32 patients with stage I/IIE thyroid DLBCL. Their median age was 66 years, the male/female ratio was 10/22. RESULTS As to the cellular immunophenotype, CD20 was positive in 31/32, CD5 in 0/32, CD10 in 4/32, CD2...

Journal: :Blood 2005
Silvia Bea Andreas Zettl George Wright Itziar Salaverria Philipp Jehn Victor Moreno Christof Burek German Ott Xavier Puig Liming Yang Armando Lopez-Guillermo Wing C Chan Timothy C Greiner Dennis D Weisenburger James O Armitage Randy D Gascoyne Joseph M Connors Thomas M Grogan Rita Braziel Richard I Fisher Erlend B Smeland Stein Kvaloy Harald Holte Jan Delabie Richard Simon John Powell Wyndham H Wilson Elaine S Jaffe Emili Montserrat Hans-Konrad Muller-Hermelink Louis M Staudt Elias Campo Andreas Rosenwald

Gene-expression profiling has identified 3 major subgroups of diffuse large B-cell lymphoma (DLBCL): germinal center B-cell-like (GCB), activated B-cell-like (ABC), and primary mediastinal DLBCL (PMBCL). Using comparative genomic hybridization (CGH), we investigated the genetic alterations of 224 cases of untreated DLBCL (87 GCB-DLBCL, 77 ABC-DLBCL, 19 PMBCL, and 41 unclassified DLBCL) previous...

2014
Tian Lin Bruno D. Abrahao Robert D. Kleinberg John Lui Wei Chen

In online learning, a player chooses actions to play and receives reward and feedback from the environment with the goal of maximizing her reward over time. In this paper, we propose the model of combinatorial partial monitoring games with linear feedback, a model which simultaneously addresses limited feedback, infinite outcome space of the environment and exponentially large action space of t...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2011
Michael R Green Stefano Monti Riccardo Dalla-Favera Laura Pasqualucci Nicole C Walsh Marc Schmidt-Supprian Jeffery L Kutok Scott J Rodig Donna S Neuberg Klaus Rajewsky Todd R Golub Frederick W Alt Margaret A Shipp John P Manis

We utilized gene expression profiling of a comprehensive panel of purified developmentally defined normal murine B cells to identify unique transcriptional signatures for each subset. To elucidate transcription factor activities that function in a stage-specific fashion, we used gene sets that share transcription factor targets and found that germinal center B cells had a robust enrichment of u...

Journal: :Systems 2023

Green consumption is an important tool to accelerate the circular economy and promote sustainable development. The identification of critical influencing factors for green key promoting behavior (GCB). Firstly, based on joint framework theory planned (TPB) attitude–behavior–context (ABC) theory, we summarized 32 from six dimensions: consumer attitude, cognitive factors, sense responsibility, ec...

2012
Apinan Aurasopon

This paper proposes a resonant dc link in PWM ac chopper. This can solve the spike problems and also reduce the switching loss. The configuration and PWM pattern of the proposed technique are presented. The simulation results are used to confirm the theory. Keywords—PWM ac chopper and Resonant dc link.

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