Phenotypic heterogeneity is widely observed in cancer cell populations. Here, to probe this heterogeneity, we developed an image-guided genomics technique termed spatiotemporal genomic and cellular analysis (SaGA) that allows for precise selection and amplification of living and rare cells. SaGA was used on collectively invading 3D cancer cell packs to create purified leader and follower cell l...

We consider the problem of having a group of nonholonomic mobile robots equipped with omnidirectional cameras maintain a desired leader-follower formation. Our approach is to translate the formation control problem from the configuration space into a separate visual servoing task for each follower. We derive the equations of motion of the leader in the image plane of the follower and propose tw...

Traditionally, cam-follower systems are designed by assuming a constant camshaft speed. Nevertheless, all cam-follower systems, especially high-speed systems, exhibit some camshaft speed fluctuation (despite the presence of a flywheel) which causes distorted follower motions and subsequent dynamical problems. The authors previously proposed two methods to overcome these problems: (i) the synthe...

We consider the problem of distributed leader-follower formation control for nonholonomic mobile robots equipped with central-panoramic cameras. By specifying the desired formation in the image plane, we translate the control problem into a separate visual servoing task for each follower. We use a rank constraint on the omnidirectional optical flows across multiple frames to estimate the positi...

The topic of this paper is to control and synchronize sphere-shaped spacecrafts in a leader-follower synchronization scheme. In order to achieve this objective, a nonlinear mathematical model of the vehicles has been developed. The design is based on rigid body dynamics where the vessel is actuated by means of three orthogonally mounted reaction wheels. The attitude dynamics is derived using Eu...

Follower loads, i.e. loads which depend on the boundary displacements by definition, frequently occur in finite deformation boundary-value problems. Restricting to axisymmetrical applications, we provide analytical and numerical solutions for a set of problems in compressible Neo-Hookean materials so to serve as benchmark problems for verifying the accuracy and efficiency of various FE methods ...

We consider a single-item, independent private value auction environment with two bidders: a leader, who knows his valuation, and a follower, who privately chooses how much to learn about his valuation. We show that, under some conditions, an ex-post efficient revenuemaximizing auction—which solicits bids sequentially—partially discloses the leader’s bid to the follower, to influence his learni...

Leadership research that examines follower characteristics as a potential moderator of leadership effectiveness is lacking. Within Bass's (1985) transformational leadership framework, we examined follower narcissism as a moderator of the coach behavior-coach effectiveness relationship. Youth athletes (male = 103, female = 106) from the Singapore Sports Academy (mean age = 14.28, SD = 1.40 years...

The paper studies the formation merging problem for a leader-follower network. That is, how to control a team of agents called followers so that they are merged with a team of agents called leaders to form a larger globally rigid formation. Under the premise that a group of leaders move in a globally rigid formation with their synchronized velocity known to the followers, we show that the follo...

In this paper, we present the design, modelling and experimental validation of a novel experimental cam-follower rig for the analysis of bifurcations and chaos in piecewise-smooth dynamical systems with impacts. Experimental results are presented for a cam-follower system characterized by a radial cam and a flat-faced follower. Under variation of the cam rotational speed, the follower is observ...