BACKGROUND The activity of the ribonucleoprotein enzyme telomerase is not detected in normal somatic cells; thus, with each cell division, the ends of chromosomes consisting of the telomeric repeats TTAGGG progressively erode. The current model gaining support is that telomerase activity in germline and immortal cells maintains telomere length and thus compensates for the "end-replication probl...

BACKGROUND Reduction mammaplasty (RM) is among the commonly performed procedures by plastic surgeons. Occult breast cancers are rarely detected in these specimens. The purpose of the study was to describe histopathological evaluation of reduction mammaplasty specimens to detect occult breast cancer in Southern Iran. METHODS The histological diagnosis of 350 RM specimens from 175 patients...

INTRODUCTION Fibroadenoma is the most common benign tumor of the female breast with the highest incidence before age 30. Fibroadenoma may be associated with fibrocystic changes, proliferative epithelial changes, and extremely rarely, with non-invasive and invasive cancer. CASE PRESENTATION We present a rare case of a 39 years old female with invasive ductal carcinoma arising within fibroadeno...

BACKGROUND Prevalence of breast cancer in Asian developing countries is much lower than western developed countries. The main aim of this study was to measure breast cancer prevalence in a defined population of Iran. METHODS A total of 25201 women who were under coverage of "Imam Khomeini Relief Foundation (IKRF)", which is an organization for delivering supportive social and cultural service...

Breast cancer is one of the commonest cancers among women in Malaysia. The relation between lifestyle practices and the risk of breast cancer in Chinese women aged 21-55 years were assessed using data collected from June to October 2001, via a face-to face interview in a case control study in the Breast Clinics of Kuala Lumpur Hospital and University Malaya Medical Centre. A total of 89 cases w...

Phyllodes tumors are very rare tumors of the breast. They usually present in fast-growing mass form and are confused with diagnosis of fibroadenoma in daily clinical practice. The adequacy of treatment and follow-up may be hesitated in some centers which are not engaged with breast disease spesifically due to post-surgical excisional diagnosis in usual. In this article, we have reviewed the tre...

OBJECTIVE To describe the clinicopathologic profile of breast disease in Jamaica. METHODS The Jamaican Breast Disease Study is an ongoing prospective, multidisciplinary investigation of breast disease at the University Hospital of the West Indies (UHWI). The initial phase was a prevalence survey comprising all consenting patients referred to the Surgical Outpatient Department (SOPD) UHWI, for...