نتایج جستجو برای: expanded disability status

تعداد نتایج: 528759  

2017
Nora E Fritz Jennifer Keller Peter A Calabresi Kathleen M Zackowski

At least 85% of individuals with multiple sclerosis report walking dysfunction as their primary complaint. Walking and strength measures are common clinical measures to mark increasing disability or improvement with rehabilitation. Previous studies have shown an association between strength or walking ability and spinal cord MRI measures, and strength measures with brainstem corticospinal tract...

Journal: :The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2004
Fraser Moore Christina Wolfson Lubo Alexandrov Yves Lapierre

BACKGROUND Quality of life instruments provide information that traditional outcome measures used in studies of multiple sclerosis do not. It is unclear if longer, disease-specific instruments provide more useful information than shorter, more general instruments, or whether patients prefer one type to another. METHODS We conducted a cross-sectional study of quality of life in a multiple scle...

Journal: :Archives of neurology 2005
J Sastre-Garriga G T Ingle D T Chard Lí Ramió-Torrentà M A McLean D H Miller A J Thompson

BACKGROUND Abnormalities in normal-appearing brain tissues may contribute to disability in primary progressive multiple sclerosis (PPMS), where few lesions are seen on conventional imaging. OBJECTIVES To evaluate the mechanisms underlying disease progression in the early phase of PPMS by measuring metabolite concentrations in normal-appearing white matter (NAWM) and cortical gray matter (CGM)...

Journal: :Brain : a journal of neurology 2016
Johannes Lorscheider Katherine Buzzard Vilija Jokubaitis Tim Spelman Eva Havrdova Dana Horakova Maria Trojano Guillermo Izquierdo Marc Girard Pierre Duquette Alexandre Prat Alessandra Lugaresi François Grand'Maison Pierre Grammond Raymond Hupperts Raed Alroughani Patrizia Sola Cavit Boz Eugenio Pucci Jeanette Lechner-Scott Roberto Bergamaschi Celia Oreja-Guevara Gerardo Iuliano Vincent Van Pesch Franco Granella Cristina Ramo-Tello Daniele Spitaleri Thor Petersen Mark Slee Freek Verheul Radek Ampapa Maria Pia Amato Pamela McCombe Steve Vucic José Luis Sánchez Menoyo Edgardo Cristiano Michael H Barnett Suzanne Hodgkinson Javier Olascoaga Maria Laura Saladino Orla Gray Cameron Shaw Fraser Moore Helmut Butzkueven Tomas Kalincik

A number of studies have been conducted with the onset of secondary progressive multiple sclerosis as an inclusion criterion or an outcome of interest. However, a standardized objective definition of secondary progressive multiple sclerosis has been lacking. The aim of this work was to evaluate the accuracy and feasibility of an objective definition for secondary progressive multiple sclerosis,...

Journal: :Journal of rehabilitation research and development 2011
Saisho Mangla Seema Jain Stephen Selkirk

Multiple sclerosis (MS) is a chronic disease in which disability progresses over time. Progressive forms of MS have a poor prognosis, are associated with greater levels of disability and, unfortunately, are unresponsive to current treatments. Here, we have reviewed the management of 100 patients with MS. The majority of these patients had progressive disease, Expanded Disability Status Scale sc...

حسن قاسمی, , سید مسعود نبوی, , شهریار پورفرزام, ,

Background: Multiples sclerosis is a common demyelinating disease of CNS and the main cause of disability in young adults all over the world so any research in different aspects of the disease has great value. researches in Iran are few in quantity and low in sample size. To determine clinical course and prognosis of the disease in Iranian MS patients we have studied these items in a considerab...

Journal: :Academic radiology 2001
J K Udupa L G Nyúl Y Ge R I Grossman

RATIONALE AND OBJECTIVES Multiple sclerosis (MS) is an acquired disease of the central nervous system. Several clinical measures are commonly used to express the severity of the disease, including the Expanded Disability Status Scale and the ambulation index. These measures are subjective and may be difficult to reproduce. The aim of this research is to investigate the possibility of developing...

Journal: :The Egyptian Journal of Neurology, Psychiatry and Neurosurgery 2021

Abstract Background About 40–70% of patients with multiple sclerosis (MS) develop cognitive impairment (CI) throughout their life. We aim to study the influence MS on changes. This is a case–control fifty who met revised 2017 Mc Donald Criteria and age- sex-matched healthy subjects. The Expanded Disability Status Scale (EDSS) was used assess degree disability, Montreal Cognitive Assessment (MoC...

Journal: :International journal of MS care 2023

Abstract Background Poor sleep quality and disorders are more prevalent in individuals with multiple sclerosis (MS) than the general population. has been correlated worse MS outcomes. Sleep efficiency (SE) is one of most sensitive markers quality. There very little written about SE other polysomnography (PSG) parameters measures. Methods This a retrospective review 280 consecutive evaluated by ...

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