نتایج جستجو برای: dickkopf

تعداد نتایج: 961  

2017
Roxana Rubio Vargas Enrique Melguizo Madrid Concepción González Rodríguez Federico Navarro Sarabia Carmen Dominguez Quesada Rafael Ariza Ariza Victoria Navarro Compán

Background: Axial spondyloarthritis (axSpA) is characterized by new bone formation. The complex systems underlying this process involve Wnt-signaling pathway. It has been observed that serum levels of dickkopf-1 (DKK-1), an important inhibitor of Wnt-signaling, are decreased in patients with axSpA. However, these data are from studies including only patients with long-standing disease. The aim ...

2010
Chang-Yi Cui Makoto Kunisada Yulan Piao Victoria Childress Minoru S. H. Ko David Schlessinger

The mouse hair coat comprises protective "primary" and thermo-regulatory "secondary" hairs. Primary hair formation is ectodysplasin (Eda) dependent, but it has been puzzling that Tabby (Eda(-/y)) mice still make secondary hair. We report that Dickkopf 4 (Dkk4), a Wnt antagonist, affects an auxiliary pathway for Eda-independent development of secondary hair. A Dkk4 transgene in wild-type mice ha...

Journal: :Indian Journal of Pharmaceutical Sciences 2022

To study the autophagy and mechanism of phosphatidylinositol-3-kinase/protein kinase B/mammalian target rapamycin signaling pathway in directional differentiation mesenchymal stem cells to provide basic research results for its application medical field is main objective study. The lung bone marrow mice were used as experimental materials. materials divided into five groups according settings n...

2015

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