Introduction: Malaria has been a major public health problem plaguing India for centuries and about 95% of Indian population is residing in malaria endemic regions. The proportion of the Pf % has gradually increased from 39% in 1995 to 65% in 2014. Periodic clinical profiling studies may help us in understanding of the changing pattern of the disease, complication rate and emerging drug resista...

The Orissa state on the east coast of India is endemic for malaria for decades1. The state with a population of 3.6%, contributes about 22% of all malaria cases, 43% of the Plasmodium falciparum cases and 33% of total malaria related deaths in the country. Out of 30 districts in Orissa 27 are endemic for malaria and the average annual parasite incidence (API) for the state is 18.6 (+ 13.7). The...

The 2014 malaria epidemiological data reported through the annual malaria statistics reporting system were collected and analyzed. A total of 3 078 malaria cases were reported in 680 counties of 30 Provinces/ Municipalities/Autonomous Regions (P/M/A)(except Inner Mongolia) in 2014, decreased by 25.4% compared with the 4 128 cases in 2013. The incidence rate was 0.022 6/10 000. More cases distri...

Spontaneous splenic rupture in complicated malaria is an uncommon cause of hemoperitoneum in the tropics. The exact incidence of splenic rupture is unknown, largely due to under-reporting, but has been estimated at ∼2%. Its pathophysiology is linked to the formation of a subcapsular hematoma. Upon rupture, patients present with features of shock and peritonitis and in most cases (95%), computed...

Patient, A. A., aged 24 years, was admitted in the emergency ward of the Medical College Hospital on the 5th April, 1936, with a history of high quotidian fever for 5 days. The immediate cause of his seeking admission was the appearance of a peculiar erythematous rash all over his body without any sensation of itching. This rash appeared on the fourth day of the fever; his eyes were congested a...

INTRODUCTION To report a case of ofloxacin-associated leucopoenia, which occurred in a patient of falciparum malaria shortly after administration and resolved following discontinuation of the drug. CASE PRESENTATION A 44 year old female was admitted in circulatory shock with a diagnosis of falciparum malaria, suffering from fever, diarrhoea and vomiting. After successful resuscitation she was...

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The antagonism, by neostigmine, of neuromuscular blockade produced by either Org NC 45 or pancuronium was studied in 29 anaesthetized patients during a continuous infusion of the myoneural blocker. The ED50 of neostigmine (dose which produced a 50% antagonism) when antagonizing Org NC 45 and pancuronium was 0.011 mg kg-1 and 0.010 mg kg-1 respectively. The dose-response relationships for the an...