Introduction: Lung and colorectal carcinoma are commonly found in cancer often cause mortality worldwide. Colorectal (CRC) is the third most common of death. Although multiple primary cancers can exist, these two malignancies rarely happen simultaneously. This case report shows a patient diagnosed with squamous cell lung rectal adenocarcinoma metastases to liver, ocular, cerebrum. Case: A 54-ye...

Background: Colorectal and breast carcinoma are frequently diagnosed cancers. At advanced stages, cancers metastasize to certain organs resulting in loss of function these organs, eventually death. Therefore, there is a specific need for the prognosis Currently, microRNAs (miRNAs), have emerged as new target cancer-specific biomarker. Objective: To examine expression miRNA primary metastatic co...

The prognostic relevance of innate immune cells infiltrating colorectal carcinoma lesions is highly debated. By evaluating the expression of myeloperoxidase (MPO) as a marker of neutrophil granulocytes in a large cohort of colorectal carcinoma specimens, we have observed that robust tumor-infiltration by MPO+ cells correlates with improved patient survival independently of other histopathologic...

Neuroendocrine tumor (NET) is the most common tumors of appendix which usually found incidentally. Synchronous neuroendocrine and colonic carcinoma has been reported in previous case reports. The actual incidence these synchronous need to be determined by reviewing reports include appendectomy as part oncological colorectal operations.

AIM: To analyse the Chibby expression and its function in colon carcinoma cell lines and colorectal carcinoma

Telomere shortening and telomerase activation occur frequently in cases of colorectal carcinoma. In this study, we correlated the clinicopathological parameters with the telomere length in colorectal carcinomas, colonic polyps, and normal colonic tissues. We also investigated whether the telomere length changes reflect the biologic behavior of tumors and different modes of tumor development. Te...

background: bax and bcl-2 are the major members of bcl-2 family whose play a key role in tumor progression or inhibition of intrinsic apoptotic pathway triggered by mitochondrial dysfunction. therefore, the balance between pro- and anti-apoptotic members of this family can determine the cellular fate. methods: in this study, the relative level of mrna expression of bax and bcl-2 genes was deter...

The purpose of these studies was to determine whether blood monocytes of patients with different stages of colorectal carcinoma could be activated by various immunomodulators to become tumor cytolytic. Monocytes obtained from 12 colorectal carcinoma patients and 8 normal donors were incubated in vitro with free or liposome-encapsulated agents. The cytotoxic properties of the monocytes were dete...

background: colorectal adenocarcinoma is one of the most prevalent and treatable malignancies of the gastrointestinal tract. recent in vitro studies have demonstrated the anticancer effect of calendula officinalis extract on a tumor cell line derived from colorectal cancers. the inhibitory effect of this extract ranges from 70- 100% and an in vitro study has demonstrated that calendula officina...