Using the spectrum data for quality prediction always suffers from noise and colinearity, so variable selection method plays an important role to deal with spectrum data. An efficient elastic net with regression coefficients method (Enet-BETA) is proposed to select the significant variables of the spectrum data in this paper. The proposed Enet-BETA method can not only select important variables...

a massive sequencing approach of a cDNA library, the whole set of Hox genes of the chondrichthyan, Scyliorhinus canicula. We have sequenced seven BAC clones that include all of the HoxA, HoxB and HoxD clusters. The transcriptomic data suggests that no HoxC genes have been maintained in this species. The expression of the posterior Hox genes was studied by insitu hybridization and showed that al...

A physical model of electronic effects in the QSAR of benzene derivatives, together with a regression technique for finding predictive equations, is presented. The model is simple, based on the quantum theoretic description of the benzene molecule, and accounts for the variance in activity of hallucinogenic phenylalkylamines as well as a classical description in terms of electronic (atomic char...

The genetics of the ciliate Tetrahymena thermophila are richer than for most other eukaryotic cells, because Tetrahymena possesses two genomes: a germline (micronuclear) genome that follows a Mendelian model of genetic transmission and a somatic (macronuclear) genome, derived from the micronuclear genome by fragmentation, which follows a different genetic transmission model called phenotypic as...

U ntil recently, it was assumed that the order of gene sequences within modern maize would be virtually invariant. Recent discoveries have shown that gene colinearity is not always the case. Several laboratories (1–3) have found DNA regions rich in gene sequences that are present in some maize inbred lines but absent at homologous sites in other lines. This variation, termed ‘‘intraspecific vio...

The behavior of Lewis acidic metal ions in multimetallic systems has become a subject intense interest recent years. Parametrizing the these nonaqueous conditions, commonly used field, is challenging due to lack direct measures acidity polar organic solvents. Here, we report use triphenylphosphine oxide (TPPO) as 31P nuclear magnetic resonance (NMR) probe quantify library triflate salts using G...