نتایج جستجو برای: coculture
تعداد نتایج: 8213 فیلتر نتایج به سال:
Several signaling pathways and transcription factors control the cell fate in its in vitro development and differentiation. The orchestrated use of these factors results in cell specification. In coculture methods, many of these factors secrete from host cells but control the process. Today, transcription factors required for retinal progenitor cells are well known, but the generation of these ...
OBJECTIVE To investigate whether human T lymphotropic virus type I (HTLV-I) directly infects salivary gland epithelial cells (SGECs) and induces the niche of the salivary glands in patients with Sjögren's syndrome (SS). METHODS SGECs were cultured with the HTLV-I-producing CD4+ T cell line HCT-5 or with Jurkat cells. Antibody arrays, immunofluorescence analysis, and enzyme-linked immunosorben...
BACKGROUND The mechanism responsible for cardiac hypertrophy is currently conceptualized as having 2 components, mediated by cardiac myocytes and nonmyocytes, respectively. The interaction between myocytes and nonmyocytes via growth factors and/or cytokines plays an important role in the development of cardiac hypertrophy. We found that cardiac myocytes showed hypertrophic changes when cocultur...
HEMODYNAMICS play an important role in the focal nature of atherosclerosis. Mounting evidence has demonstrated that fluid shear stress is intimately involved in the biological activities of vascular endothelial cells (ECs). However, the role of neighboring smooth muscle cells (SMCs) in modulating the endothelial phenotype in the presence of shear stress remains undefined. Emerging EC and SMC co...
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