نتایج جستجو برای: chronic allograft dysfunction
تعداد نتایج: 644743 فیلتر نتایج به سال:
BACKGROUND The term chronic allograft nephropathy (CAN) was deleted in the Eighth Banff Classification and two new categories were introduced: chronic T-cell-mediated rejection (CTMR) and chronic active humoral rejection (CAHR). The aim of this study was to revise our CAN cases diagnosed in the last 4 years, analyse allograft survival rates and identify types of infiltrating cells in the differ...
In the past 15 years, short-term success rates for allografts of kidney, heart, liver, and kidney/pancreas have reached unprecedented levels largely due to cyclosporine-based immunosuppressive regimens. Most transplant centers around the world achieve 85 to 90% one-year graft survival for kidney transplants and very few patients suffer loss of life because of modern medical management [1, 2]. T...
Affiliations: Clinique Universitaire de Pneumologie, Pôle de Cancérologie, Médecine Aiguë et Communautaire, CHU Grenoble, Inserm1055, Grenoble, Université Joseph Fourier, Grenoble, European Institute for Systems Biology and Medicine, EISBM, Lyon, Institut du Thorax, Inserm UMR1087, CNRS UMR629, Service de Pneumologie, CHU de Nantes DHU2020, Nantes, Université de Nantes, Nantes, Université Josep...
Cardiac allograft vasculopathy is the most aggressive form of atherosclerosis in humans and is the leading cause of death after the first year of heart transplantation. Endothelial dysfunction is a major contributing factor to the acceleration of coronary vascular disease in these individuals. A reflection of this endothelial dysfunction is the severe impairment in endothelium-dependent vasodil...
Chronic lung allograft dysfunction (CLAD) is, in one sense, a term without a true consensus definition, although its common usage in the field of lung transplantation implies a base understanding throughout the community that it describes a lung allograft that does not work (well) [1]. There appears to be general agreement that CLAD most commonly occurs in a time-dependent fashion after transpl...
The principal cause of delayed renal failure after transplantation is interstitial fibrosis and tubular atrophy (IF/TA). Identification of all possible causes of IF/TA and improvement of the methods of specific treatment of such cases will be important issues for renal transplantation medicine in the future. Evidence to suggest that the epithelial-mesenchymal transition (EMT), alongside IF/TA, ...
Chronic liver allograft dysfunction (CLAD) remains the most common cause of patient morbidity and allograft loss in liver transplant patients. However, the pathogenesis of CLAD has not been completely elucidated. By establishing rat CLAD models, in this study, we identified the informative CLAD-associated genes using isobaric tags for relative and absolute quantification (iTRAQ) proteomics anal...
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