Sinonasal sarcoidosis in the head and neck region is infrequent. Its occurrence can be either isolated in combination with other systems. The literature reveals that the occurrence of sinonasal sarcoidosis without lung involvement is rare. In general, sarcoidosis is a chronic non-caseating granulomatous disease of unknown origin, often identified after biopsy. In this article, we report on a be...

Sarcoidosis is an inflammatory disease with unknown cause characterized by non-caseating granuloma formations. It may present with bilateral hilar lymphadenopathy, skin lesions, eye and musculoskeletal system involvement. Hypercalcemia and hypercalciuria are important electrolyte imbalances resulting from sarcoidosis and sometimes they may cause nephrolitiasis and kidney failure. Hyponatremia, ...

A 37-year-old woman presented with a 6 months history of headaches and memory impairment. Examination showed no neurological deficit with normal vision. MRI scans showed an enlarged optic chiasm. There was no dural or leptomeningeal enhancement or hydrocephalus. Open biopsy of the suprasellar mass showed non-caseating chronic granulomatous inflammation compatible with sarcoidosis. Systemic feat...

The granulomas of sarcoidosis and non-caseating tuberculosis show similar cell-types: two forms of epithelioid cells, A and B, giant cells, lymphocytes and 'activated' mononuclear cells. The morphology of epithelioid cells suggests that they are primarily biosynthetic rather than phagocytic. The relationship of these various cells to each other is discussed and the following sequence of granulo...

warfarin induced skin necrosis is a rare complication associated with the use of oral ‎anticoagulants. most patients develop this complication at the initiation of therapy. the complication is ‎usually associated with an underlying thrombophilia. here we describe a case of a 75 year old ‎patient who developed skin necrosis in her both breasts during warfarin treatment for a ‎deep vein thrombosi...

Sarcoidosis is an idiopathic multisystemic disorder with variable cutaneous presentations that are classified as specific or non-specific according to the presence of non-caseating granulomas on histologic examination. Specific manifestations can include papules, scar sarcoidosis, ulcers, or even alopecia. Herein, we present a case of cutaneous sarcoidosis that presented as multiple erythematou...

INTRODUCTION Sarcoidosis is a chronic systemic disease of unknown etiology, characterized by non-caseating granulmas. Although lungs are involved in more than 90% of patients, extrapulmonary involvement is common (1). All organs, especially lymph nodes, liver, skin and eyes may be involved. Abdominal lymphadenopathy due to sarcoidosis has rarely been described and is usually associated with hep...

Introduction Sarcoidosis is a granulomatous disease possibly affecting all organ systems. Less than 10% of sarcoidosis patients develop symptomatic neurological involvement. Although muscular non-caseating granulomas (NCGs) can be found in up to 75% of sarcoidosis patients, muscular symptoms develop only in less than 0.5% of sarcoidosis patients. Corticosteroids (CS) are the mainstay of medical...

Purpose Sarcoidosis is a rare multi-system inflammatory disease of unknown etiology, the pathology of which is characterized by the presence of non-caseating granulomas. Neurosarcoidosis can affect any part of the peripheral or central nervous system and occurs in approximately 5-15% of all sarcoidosis patients. In this report, we present a case of isolated neurosarcoidosis in a child manifeste...