We examined the effects of the angiotensin-converting enzyme inhibitor perindopril and the beta-blocker propranolol on dilator responses of cerebral arterioles in chronic hypertension. Dilator responses to acute hypotension were examined in untreated Wistar-Kyoto rats (WKY) and stroke-prone spontaneously hypertensive rats (SHRSP) that were untreated or treated for 3 months with a low (0.3 mg. k...

Neuro-effector transmission and mechanical responses in smooth muscles of the dog iris were studied, using tension recording and microelectrode methods. Electrical stimulations evoked an initial phasic contraction followed by relaxation in both the iris sphincter and dilator muscles. Atropine selectively suppressed phasic contraction of the sphincter and relaxation of the dilator muscle, while ...

The PROTECTED TAVR trial failed to demonstrate reduction in all stroke with the Sentinel Cerebral Protection System but suggested a incidence of disabling stroke. CPS is first-generation device that protects two three cerebral vessels leaving left vertebral unprotected and does not provide full body protection allowing debris flow into descending aorta. Emboliner Embolic Catheter (Emboline, Inc...

We previously demonstrated that skeletal muscle blood flow is restored in the exercising forearm during experimental hypoperfusion via local dilator and/or myogenic mechanisms. This study examined the role of nitric oxide (NO) in the restoration of blood flow to the active muscles during hypoperfusion. Eleven healthy subjects (10 men/1 woman; 25 +/- 1 yr of age) performed rhythmic forearm exerc...

Using stereotaxic procedures, we electrically stimulated specific sites in the hypothalamus and midbrain of anesthetized dogs pretreated with guanethidine and atropine methonitrate. A tract in which stimulation caused noncholinergic dilator responses in the hindlimbs was identified. The course of this trace was different from that subserving cholinergic vasodilation in the hindlimb musculature....

OBJECTIVE To identify and resolve procedural issues during transgastric access for the Natural Orifice Translumenal Endoscopic Surgery (NOTES), where feasibility and safety is established in animals and humans. However, several technical problems during viscerotomy result in considerable delay or procedure failure. METHODS Gastrotomy was performed under general anaesthesia in survival canine ...

angiopancreatography (ERCP) via a gastrostomy by stomal balloon dilation through a surgical or radiological gastrostomy site has been described in a few cases [1–3]. We report here a novel technique for dilating a rigid percutaneous endoscopic gastrostomy (PEG) stoma for therapeutic ERCP. A 69-year-old man with bile duct stones was hospitalized for acute cholangitis. A gastrostomy feeding tube ...

balloon dilatation of stricture is one of the new treatment methods among patients with gastric outlet obstruction (goo). however, the prevalence and underlying etiologies of goo in various populations are different. the goal of the present study was to determine the effectiveness of endoscopic balloon dilatation and factors that would affect its success rate patients with benign etiology for g...

Background: The aim of this study is to evaluate whether the location of the balloon placement into either the cervical canal or uterine cavity during sonohysterography can affect the intensity of pain. Materials and Methods: A total of 300 infertile women undergoing sonohysterography were randomized to intracervical or intrauterine balloon placement. The examination was scheduled in the early ...