Endothelial cells (EC) express several members of the Homeobox (Hox) gene family, suggesting a role for these morphoregulatory mediators during angiogenesis. We have previously established that Hox D3 is required for expression of integrin alphavbeta3 and urokinase plasminogen activator (uPA), which contribute to EC adhesion, invasion, and migration during angiogenesis. We now report that the p...

Technical Appendix Figure. Phylogenetic analysis of B3 genotype measles virus sequences detected in India with selected global B3 genotypes. A D8 genotype sequence from Thiruvananthapuram was used as the outgroup. We performed maximum-likelihood analysis with 1,000 bootstrap replications using Kimura2-parameter correction with gamma-distributed settings. Solid red triangles indicate strains fro...

Microdeletions in the azoospermia factor (AZF) regions on the long arm of the human Y chromosome are known to be associated with spermatogenic failure. Although AZFc is recurrently deleted in azoospermic or oligozoospermic males, no definitive conclusion has been reached for the contribution of different partial AZFc deletions to spermatogenic failure. To further investigate the roles of partia...

In this paper we demonstrate a method of synthesizing oligoenes of diisopropyldipropargylmalonate, [CH2][bx][CH2] (x ) 2, 3, 4, 5), in which the “b” repeat unit is identical to the five-membered ring formed in a tail-to-tail cyclopolymerization of diisopropyldipropargylmalonate, and methylene groups are capping the ends. For example, a “degenerate” metathesis reaction between the “monomer”, [CH...

EphB receptors and their ephrin-B ligands are required for midline guidance decisions at several rostrocaudal levels of the developing CNS. In the embryonic vertebrate spinal cord, ephrin-B3 is localized to the floor plate (FP) at the ventral midline (VM), ephrin-B1 and ephrin-B2 are expressed in the dorsal spinal cord, and decussated EphB receptor-bearing commissural axons navigate between the...

Prolonged flurazepam exposure regulates the expression of selected (a1, b2, b3) GABAA receptor subunit messenger RNAs in specific regions of the hippocampus and cortex with a time-course consistent with benzodiazepine tolerance both in vivo and in vitro. In this report, the immunostaining density of six specific GABAA receptor subunit (a1, a2, b1–3 and g2) antibodies was measured in the hippoca...

The exopolysaccharide (EPS B3-15) and biosurfactant (BS B3-15), produced by the marine Bacillus licheniformis B3-15, were recently reported to possess different antibiofilm activities, with EPS being more active in preventing adhesion of Pseudomonas aeruginosa Staphylococcus aureus BS destroying their preformed biofilms on surfaces. In this study, synergistic effects two exopolymers bacterial b...

PURPOSE Activation of muscarinic receptors has been implicated in an increased risk of cataract after anticholinesterase treatment for glaucoma. The purpose of the present study was to determine the acetylcholine muscarinic receptor subtype(s) present in native human lens epithelial cells (NHLECs) and a human lens cell line, HLE-B3, and to compare the distribution in other ocular cells. METHO...

Given the importance of auxin, it has been surprisingly difficult to elucidate its biosynthetic pathways in plants. Several Trpdependent routes have been proposed, in which CYTOCHROME P450 79B2/B3 (CYP79B2/B3), YUCCA (YUC), and TRYPTOPHAN AMINOTRANSFERASE OF ARABIDOPSIS1/TRYPTOPHAN AMINOTRANSFERASE RELATED (TAA1/TAR) genes have been thought to act in separate pathways (reviewed in Zhao, 2010). ...