Free amino acids content of aqueous humor in Pakistani subjects with senile cataract is measured and results are compared with previous studies Most of the amino acids showed lower concentration than those reported for European’ and American2 subjects (JPMA 37 67, 1987).

Purpose: Fluoroquinolones are widely used antibiotics for prophylaxis of intra and postoperative infections in individuals undergoing cataract surgery. This study was designed to assess the penetration of ciprofloxacin into the ocular aqueous humor (topical only versus topical and oral

The steroid antibiotic Fucidin, or sodium fusidate, has been in use for a number of years as an antistaphylococcal agent. It has been used empirically in the treatment of intraocular staphylococcal infection, but there has been no study of the degrees of penetration of the drug into the aqueous humour in the normal intact human eye, and the present study was therefore undertaken to investigate ...

Hue Mohun, a Hindu boy, aged 12 years, was brought to the dispensary at Hungpore on the 3rd December, 1871. He had a very thin chip of bamboo accidentally fixed into the cornea of his right eye. The chip had gone through the thickness of the cornea for about a quarter of an inch, and then just protruded into the aqueous humor, but the outer end was not protruding externally. The whole length of...

Eye is second most complex organ of the body after brain. Drug delivery to the eye is the challenging task for the pharmaceutical scientists. Topical administration to the eye is the most convenient and commonly used for the pharmacological therapy. Effectiveness of the drugs can only be determined by the pharmacokinetics and pharmacodynamics correlation. Ocular pharmacokinetics is the essentia...

Richard F. Figure 1 shows a human eye without its aqueous circulation. The cornea is thickened, the anterior chamber is absent, the iris is partly atrophic, and the lens is cataractous. The picture serves as a reminder of the dependency of the health of the eye on the continuous supply of aqueous humor that circulates through its chambers. It is surprising that it was not known until recently t...

Facility of bulk aqueous humor outflow via conventional channels, true facility, and pressure sensitive suppression of aqueous humor inflow, pseudofacility, were measured by constant pressure perfusion in 24 eyes of 12 rhesus monkeys. True facility was found to have a mean value of 0.55 ,uL minr mm. Hg~ and pseudofacility was found to have a mean value of 0.12 p.L minr mm. Hg-. This figure is i...

Endophthalmitis is an infection of the vitreous or aqueous humor of the eye. Although it rarely occurs in the neonatal period it has been previously diagnosed in preterm infants.Endogenous endophthalmitis is when eye infection is secondary to septicemia and represent 20% of the cases of endophthalmitis. Pseudomonas aeruginosa is responsible for more than 75% of invasive neonatal eye infections....

When newer tables for parameters in Grant's formula for tonography are used, one obtains far higher values for the outflow facility than those generally accepted. The aim of this iinvestigation has, therefore, been to test the validity of the tonography formula. The outflow facility determined by constant-rate perfusion in enucleated eyes has been compared with the results of tonography on the ...