نتایج جستجو برای: antinociceptive activities

تعداد نتایج: 380840  

Journal: :medical journal of islamic republic of iran 0
h hosseinzadeh from the department of pharmacodynamy and toxicology, faculty o/pharmacy, mashhad university of medical sciences, p.o. box 91775-1365, mashhad, i.r. iran. me shooshtari

there are several reports that adenosine and carbamazepine have pharmacodynamic interaction. i n this study the antinociceptive interaction o f these two agents was evaluated in mice by the hot plate test. agents were injected intraperitoneally. 0.2 and 0.4 mg/kg doses of r-phenylisopropyladenosine (r-pia) substantially showed antinociceptive effects. carbamazepine had antinociceptive actions e...

Journal: :Anais da Academia Brasileira de Ciencias 2017
Ethel A Wilhelm Ana Teresinha Ferreira Mikaela P Pinz Angélica S Dos Reis Ane G Vogt Andre L Stein Gilson Zeni Cristiane Luchese

The present study investigated the antioxidant effect of a new class of quinoline derivatives (a-d) on assays in vitro. Lipid peroxidation, thiol peroxidase-like and free radical scavenging activities were determined to evaluate antioxidant activity of compounds. Thiol oxidase-like and δ-aminolevulinate dehydratase activities were performed as a toxicological parameter. A second objective of th...

The plants of the genus Polygala (Polygalaceae) are employed in folk medicine for the treatment of several pathologies, including disorders of the bowel and kidney, as anesthetic, expectorant and anti-inflammatory. The present study was undertaken to investigate the antiedematogenic and antinociceptive activities of methanolic extract of Polygala boliviensis A. W. Benn (MEPB) in mice. The antin...

2014
Neeta Chaudhary Shalini Tripathi

Psidium guajava Linn. (Guava) is used not only as food but also as folk medicine in subtropical areas around the world because of its pharmacologic activities. In particular, the leaf extract of guava has traditionally been used for the treatment of diabetes in East Asia and other countries. Many pharmacological studies have demonstrated the ability of this plant to exhibit antioxidant, hepatop...

Journal: :Zeitschrift fur Naturforschung. C, Journal of biosciences 2008
Rogério Corrêa Bruna Proiss Fenner Fátima de Campos Buzzi Valdir Cechinel Filho Ricardo José Nunes

Chalcones belong to a class of alpha,beta,-unsaturated aromatic ketones which occur abundantly in nature, especially in plants. They are promising and interesting compounds due to their vast applications in pharmaceuticals, agriculture and industry. Several studies have shown that these compounds exert important biological activities in different experimental models. The present work deals with...

Journal: :Current Biology 2014
Yan Zhang Chaoran Wang Lien Wang Gregory Scott Parks Xiuli Zhang Zhimou Guo Yanxiong Ke Kang-Wu Li Mi Kyeong Kim Benjamin Vo Emiliana Borrelli Guangbo Ge Ling Yang Zhiwei Wang M. Julia Garcia-Fuster Z. David Luo Xinmiao Liang Olivier Civelli

BACKGROUND Current pain management is limited, in particular, with regard to chronic pain. In an attempt to discover novel analgesics, we combined the approach developed to characterize traditional Chinese medicine (TCM), as part of the "herbalome" project, with the reverse pharmacology approach aimed at discovering new endogenous transmitters and hormones. RESULTS In a plant used for centuri...

Objective: The genus Marrubium is used for treatment of joint pain, gout, stomach-ache and colic in Iranian Traditional Medicine. Marrubium astracanicum Jacq. (M. astracanicum) is a native species in the flora of Iran. The aim of this study was to evaluate the antinociceptive properties of various extracts of aerial parts of M. astracanicum.Materials and Methods: Antinociceptive activities of t...

Objective: Berberis vulgaris has antioxidant, hepato--renal protective, antibacterial, lipid lowering, anti-inflammatory and antinociceptive activities. The genus Berberis, has another member called Berberisintegerrima which has not been studied for antinociceptive activity and therefore, this study was aimed to examine the antinociceptive effect oftotal extract and alkaloid fractions of Berber...

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