OBJECTIVE The purpose of this study was to compare the clinical efficacy of articaine at 4% (epinephrine 1:100,000) with bupivacaine at 0.5% (epinephrine 1:200,000) for surgical extraction of impacted mandibular third molars. STUDY DESIGN This was a randomized, double blind, split-mouth, clinical trial. Thirty-six patients took part and underwent extraction of 72 lower third molars. The varia...

BACKGROUND AND OBJECTIVES Local anesthetics are used broadly to prevent or reverse acute pain and treat symptoms of chronic pain. Local anesthetic-induced cardiotoxic reaction has been considered the accidental event without currently effective therapeutic drugs except for recently reported intralipid infusion whose possible mechanism of action is not well known. CONTENTS Cardiolipin, an anio...

  Clonidine, an α2-adrenergic receptor agonist not only induces analgesia but also prolongs the effects of local anesthetic substances. In the present study the effects of clonidine on spontaneous and formalin-induced electrical activity from dorsal skin nerve were investigated. The results showed that clonidine (0.5 mM) decreased the formalin effect on electrical nerve activity whereas clonidi...

In general, the anesthesia in neonates involves high risk. Although hypothermic anesthesia is recommended in rats up to the age of 7 days, neonatal anesthesia for later periods has not been standardized. The present study investigated the pharmacological properties of conventional anesthetic protocols in 10-day-old SD rats. The rats were anesthetized with four anesthetics: a combination of keta...

INTRODUCTION TAB block has been used as an analgesic adjuvant in many abdominal surgeries with fair reliability, but it has never been used as an anesthetic technique. CASE PRESENTATION In this case report, a 19- year-old male underwent an open appendectomy using ultrasound-guided TAP block as a single anesthetic technique. CONCLUSIONS It was concluded that under certain circumstances TAP b...

Alcohol use poses a variety of health complications. Because alcohol consumption in the days prior to surgery can induce lower blood pressure, the anesthesiologist will need to monitor blood pressure very closely during surgery to prevent hypotension. Before surgery, it is important for anesthesiologist to be aware about the amount and timing of recent alcohol consumption. Less anesthesia shoul...

Discharge time (total recovery time) is one determinant of the overall cost of outpatient surgery. We performed this study to determine what factors affect discharge time. Details regarding patients, anesthesia, surgery, and recovery were recorded prospectively for 1088 adult patients undergoing ambulatory surgery over an 8-mo period. The contribution of factors to variability in the discharge ...