Two-sized luminescent nucleic acid-functionalized Ag nanoclusters (NCs) are implemented for the analysis and multiplexed detection of adenosine monophosphate, AMP, and of cocaine using aptamer-ligand complexes.

The selective recognition of adenosine monophosphate by a half-duplex aptamer-modified electrode leads to a simple chronocoulometric aptasensor based on the changes in surface charges.

Cells dying by apoptosis can trigger an anti-inflammatory gene response in other cells by releasing a compound called adenosine monophosphate.

Submit Manuscript | http://medcraveonline.com Abbreviations: AMP: Adenosine Monophosphate; ATP: Adenosine Triphosphate; cAMP: Cyclic Adenosine Monophosphate; CD: Cluster of Differentiation; CTLA-4: Cytotoxic T-LymphocyteAssociated Protein 4; IDO: Indoleamine 2,3-dioxygenase; IFN: Interferon; IL: Interleukin; LAG3: Lymphocyte-Activation Gene 3; TCR: T Cell Receptor; TGF-β: Transforming Growth Fa...

The interaction of a protein inhibitor with the catalytic subunit derived from adenosine 3’,5’-monophosphatedependent protein kinase is described. A kinetic analysis of casein phosphorylation in the presence of inhibitor reveals a noncompetitive interaction between the inhibitor and the catalytic subunit substrates, ATP and casein. The inhibitor does not function by destroying ATP nor by acting...

N6,O2'-Dibutyryladenosine cyclic 3',5'-phosphate plus theophylline inhibited the growth of the mouse mast cell tumor line PY 815 both in vivo and in vitro. The inhibitory effect on growth in vitro was rapidly reversed following removal of the drugs. Growth inhibition was accompanied by reduced cell surface activity and increased cell-cell adhesion. The drug-treated cells accumulated distinct me...

• Nucleic acid precursors: nucleotides make up the monomeric units of DNA and RNA. • Energy-transfer molecules: adenosine triphosphate (ATP) is the major source of cellular chemical energy. • Physiologic mediators: cyclic adenosine monophosphate (cAMP) acts as second messenger; cyclic guanosine monophosphate (cGMP) regulates many cellular events; adenosine is known to be a potent vasodilator; g...

Mutants of Vibrio parahaemolyticus defective in binding activity for adenosine 3',5'-cyclic monophosphate are described. They were selected with medium containing the nucleotide together with starch.