The new antifungal derivative posaconazole was tested against three clinical isolates of Cryptococcus neoformans var. neoformans using a broth microdilution procedure performed according to the guidelines established by the NCCLS. Posaconazole MICs were 0.125, 0.25 and 1.0 mg/L for isolates 491, 2337 and 486, respectively. To investigate the in vivo activity of this new compound, we established...

PURPOSE The long-term safety and efficacy of levetiracetam (LEV) was evaluated as add-on therapy in focal epilepsy patients (n=491) aged at least 65 years who failed at least one monotherapy. METHODS Patients (n=491) with focal epilepsy treated with at least one antiepileptic drug in monotherapy with insufficient seizure control were included in this prospective open-label study. The recommen...

BACKGROUND Residents in nursing homes (NHs) always represent potential reservoirs for Staphylococcus aureus and methicillin-resistant S. aureus (MRSA). To our knowledge, there is no epidemiological information up till now that describes the prevalence and molecular characteristics of S. aureus in nursing home residents in Shanghai, China. METHODS Four hundred and ninety-one unique residents f...

Sajal Kumar Saha*, A. K. Azad Chowdhury, Sitesh Chandra Bachar, Sreedam Chandra Das, Ruhul H. Kuddus, Md Aftab Uddin Department of Clinical Pharmacy and Pharmacology, University of Dhaka, Dhaka-1000, Bangladesh Department of Pharmaceutical Technology, University of Dhaka, Dhaka-1000, Bangladesh Department of Genetic Engineering and Biotechnology, University of Dhaka, Dhaka-1000, Bangladesh Asia...

Department of Veterinary Surgery & Radiology. College of Veterinary Science and Animal Husbandry. Anjora, Durg, C.G 491 011, India. * Correspodning author present address : Div. of Clinical Veterinary Medicine Faculty of Veterinary Sciences & Animal Husbandry, SKUAST-K Shuhama-190 006, India * Corresponding author E-mail: [email protected] Published online at www.veterinaryworld.org on 25-...

http://dx.doi.org/10.1016/j.displa.2014.11.003 0141-9382/ 2014 Elsevier B.V. All rights reserved. ⇑ Corresponding author at: Institut des Sciences du Mouvement, UMR CNRS 7287, Aix-Marseille Université, 163 avenue de Luminy, 13009 Marseille, France. Tel.: +33 491 17 04 55. E-mail address: [email protected] (R.J. Bootsma). Olivier Borg , Remy Casanova , Camille Coton , Charlie Barla , R...

To develop and evaluate a real-time Artificial Intelligence (AI) based system to automatically keep track of acquired images; check that the images conform imaging protocol standards, in essence, replacing human peer reviewer. We developed an AI (ScanNav) which (1) checks completeness record during fetal anomaly screening, ensuring all 19 required views are recorded; (2) assesses quality these ...

BACKGROUND The incidence of childhood obesity and type 2 diabetes is an increasing problem in Europe. We determined the prevalence of impaired glucose regulation in a predominantly Caucasian cohort of 491 children and adolescents with obesity. METHODS Fasting glucose and insulin levels were determined in all 491 subjects. Patients with an abnormal fasting glucose or with additional risk facto...