BACKGROUND Trypanosomiasis is a neglected tropical disease with complex clinical manifestations, tedious diagnosis, and difficult treatments. The drugs available for the treatment of this endemic disease are old, expensive, and associated with other problems including safety and drug resistant parasites. Therefore, there is an urgent need for the development of new, effective, cheap, and safe d...

To investigate the effect of Flaxseeds (Flax) or vitex Agnus-castuson (Vitex), a total 180 aged hens (58 weeks age) were divided into 5 treatment groups with 36 each as followe: 2 and 3 fed basal diet supplemented 1 g Flax/kg, respectively. And group 4 2.5 Vitex/kg, While was served control group. The experiment period lasted for two months. Flax Vitex in hens’ rations resulted significant (p ≤...

Anti-inflammatory activity of Indonesian polyherbal product containing Curcuma zanthorrhiza and Vitex trifolia as the main ingredients in carrageenan- histamine-induced inflammation Wistar rats

Vitex mollis is used in traditional Mexican medicine for the treatment of some ailments. However, there are no studies on what happens to the anti-inflammatory activity or antioxidant properties and total phenolic content of leaves and stem extracts of Vitex mollis during the digestion process; hence, this is the aim of this work. Methanolic, acetonic, and hexanic extracts were obtained from bo...

Objective: Vitex negundo, commonly known as “nirgundi” is widely used in traditional as well as in folk medicines to cure many ailments such as fever, rheumatism, gum and skin diseases and liver disorders, etc. The present study evaluated the antioxidant potency of hydroethanolic extract of Vitex negundo leaves (VNE) in Freund’s complete adjuvant (FCA) induced arthritis. Methods: Acute oral tox...

Ten new labdane-type diterpenes were isolated from the fruit of Vitex rotundifolia L. (Verbenaceae), along with a known diterpene, vitexilactone. Their chemical structures were determined on the bases of spectroscopic data.

conclusions potent antifungal activity, make this plant an effective replacement treatment for fungal infections or fungal strains that are resistance to synthetic antifungals. results thirty-two components were identified in vitex agnus-castus eo. the main compound was alpha-pinene (19.48%). the total phenolic content of eo was determined as 82.26 ± 5.94 mg gallic acid equivalent (gae)/g eo. t...

The bee fossil record is fragmentary, making it difficult to accurately estimate the antiquity of bee-mediated pollination. Here, we describe a bee fossil [Melittosphex burmensis (new species), Melittosphecidae (new family)] from Early Cretaceous Burmese amber (approximately 100 million years before the present). The fossil provides insights into the morphology of the earliest bees and provides...

Supercritical fluid extract and ethanol extract of Vitex negundo Linn. were subjected to the chromatographic evaluation for identification of their constituents. Free radical scavenging activity of both extracts was studied by subjecting them to DPPH assay. IC(50) values of ethanol and supercritical fluid extract of Vitex negundo indicate that ethanol extract has stronger reducing potential and...