نتایج جستجو برای: vascular endothelial growth factor receptor

تعداد نتایج: 2100290  

Journal: :Hypertension 2010
Phillip S Gould Mei Gu Jianqin Liao Shakil Ahmad Melissa J Cudmore Asif Ahmed Manu Vatish

Preeclampsia is a hypertensive disorder of pregnancy caused by abnormal placental function, partly because of chronic hypoxia at the utero-placental junction. The increase in levels of soluble vascular endothelial growth factor receptor 1, an antiangiogenic agent known to inhibit placental vascularization, is an important cellular factor implicated in the onset of preeclampsia. We investigated ...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2005
Jeremy N Rich Sith Sathornsumetee Stephen T Keir Mark W Kieran Andrea Laforme Arja Kaipainen Roger E McLendon Michael W Graner B K Ahmed Rasheed Ling Wang David A Reardon Anderson J Ryan Catherine Wheeler Isaiah Dimery Darell D Bigner Henry S Friedman

PURPOSE Primary central nervous system (CNS) tumors represent a diverse group of tumor types with heterogeneous molecular mechanisms that underlie their formation and maintenance. CNS tumors depend on angiogenesis and often display increased activity of ErbB-associated pathways. Current nonspecific therapies frequently have poor efficacy in many of these tumor types, so there is a pressing need...

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2018

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