A novel family of chiral ortho-substituted BINAPO ligands (o-BINAPO) were synthesized from BINOL, and their Ru complexes were highly efficient catalysts for asymmetric hydrogenation of beta-aryl-substituted beta-(acylamino)acrylates and beta-aryl-substituted beta-keto esters. The Ru-bisphosphinite catalysts can tolerate an E/Z mixture of beta-aryl-substituted beta-(acylamino)acrylates. These hi...

Each of the twenty amino acids are represented by a graph-theoretic tree. Biomolecular descriptors are defined by graphical invariants and are used to determine similarity based on the corresponding Euclidean distances. The results verify that graph-theoretic measures independent of biochemical and biophysical descriptors are valid measures of similarity of amino acids. These results may prove ...

4-Sulfoalkanoic acids are a class of important dianionic-headed surfactants. Various 4-sulfoalkanoic acids with straight C8, C10, C12, C14, C16, and C18 chains were synthesized expeditiously through the radical addition of methyl 2-((ethoxycarbonothioyl)thio)acetate to linear terminal olefins and subsequent oxidation with peroxyformic acid. This is a useful and convenient strategy for the synth...

A Pd-catalyzed arylation of lactic acid employing 8-aminoquinoline as the directing group has been reported. The protocol is found to be compatible with a broad range of synthetically useful functional groups, thus providing a practical route to chiral β-aryl-α-hydroxy acids. Further, the new reaction has also been applied to the synthesis of pharmaceutically important α-hydroxy acids, such as ...

Background: Hops Plant (Humulus lupulus L.) plants is very beneficial has many industrial and medical applications. hops has protein, amino acids, lipids, fatty acids, sugars such as glucose and fructose, pectin, salts, wax and estrogenic compounds. So the aim of this study was to evaluate the effect of hops extracts on hormone levels and sex cells in adult mice. Materials and Methods: 40 adult...

Sunflower (Helianthus annuus) is a major oilseed crop, cultivated throughout the world, and nutritional quality of its edible oil ranks among best vegetable oils in agricultural product. In Tunisia, there lack study on biochemical characterization sunflower germplasm oil. The present was conducted to analyze content fatty acid composition 22 local introduced accessions. Results revealed signifi...

A stable essential fatty acid-deficient cell type, known as HepG2-EFD, was derived from the lipoprotein-producing human hepatoma cell line HepG2. These cells are particularly useful for quantitative studies involving essential fatty acids (n-6 and n-3 fatty acids) in secreted lipoproteins. Radiolabeled essential fatty acids can be delivered to these cells without altering the specific activity ...