Visuospatial neglect is a frequent and disabling consequence of injuries to the right hemisphere. Patients with show signs impaired attention for left-sided events, which depends on dysfunction fronto-parietal networks. After unilateral injury, such as stroke, these networks their contralateral homologs can reorganize following multiple potential trajectories, be either adaptive or maladaptive....

Callosotomy is an invasive method that used to study the role of interhemispheric functional connectivity in brain. This surgical approach technically demanding perform small laboratory animals, such as rodents, due several methodological challenges. To date, there exist two main approaches for transecting corpus callosum (CC) rodents: trephine hole(s) or unilateral craniotomy, which cause dama...

Many studies have examined the preclinical efficacy of Mg2+ therapy in models of traumatic brain injury. However, more of these studies have examined sensorimotor and motor performance than cognitive performance following injury. The present paper reviews the use of Mg2+ therapy to facilitate cognitive recovery in several models of cortical injury in the rodent. The first study examined the abi...

Traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality in young adults and children, and is a leading public health problem worldwide. In TBI, neurological impairment is caused by immediate brain tissue disruption (primary injury) and post‑injury cellular and molecular events (secondary injury) that exacerbate the primary neurological insult. However, the destructi...

this study briefly reviews the heart abnormalities in diverse intracranial pathologies, including strokes, spontaneous and traumatic subarachnoid hemorrhage and intracranial hemorrhage, and presents the results of a one-year prospective study of heart abnormalities in patients with moderate to severe head injuries and subarachnoid hemorrhage. different abnormalities such as: qt -interval, t -wa...

objective: to investigate the effects of intracranial pressure (icp) monitoring on mortality rate and functional outcome of patients with severe traumatic brain injury (tbi). methods: this was historical cohort study being performed in nemazee hospital of shiraz during a 4-year period (from 2006 to 2010) including those patients with severe tbi who had undergone care based on icp monitoring (ca...