Diabetic Neuropathy (DN) is one of the prevailing micro vascular complications diabetes which can be characterized by neuropathic pain. Streptozotocin (STZ) induced in rat has been increasingly used as a model painful diabetic neuropathy. STZ injection leads to neurotoxicity peripheral nerves that development Peripheral model. The present study was aimed at exploring protective role Tinospora c...

objective: the role of herbs against the free radicals have been put forth recently in combating many diseases. the aim of this study was to elucidate the in vitro capacity and in vivo antioxidant properties of sedimental extract of tinospora cordifolia (setc). materials and methods: setcwas subjected to in vitro chemical analysis such as 1,1-diphenyl-2-picrylhydrazyl (dpph), nitric oxide, hydr...

background: synthetic radio-protective agents like aminothiols are toxic and fda approved agent amifostine is no exception. some ayurvedic herbs have shown radioprotective potential. this study was carried out to test and compare the radioprotective potential of curcuma longa (cl) tinospora cordifolia (tc), zizyphus mauritiana (zm) and ocimum sanctum (os) against 2gy gamma irradiation in swiss ...

Background: Radiotherapy is the main modality of cancer treatment. There are many chemical radioprotectors which unfortunately have lethal or toxic effect. Therefore the search is on to find out natural plant based radioprotectors. A well known medicinal plant,which is more acceptable to the body, Tinospora cordifolia, was tested in animal tissues against gamma radiations. Radioprotectiv...

The present study was taken up to investigate the effect of petroleum ether extract of Tinospora cordifolia (Wild.) Miers, on depression in mice. The extract (50, 100 and 200 mg/kg, p.o.) was administered for 14 successive days to Swiss young albino mice (either sex) and evaluated for antidepressant-like activity using tail suspension test and forced swim test. Petroleum ether extract at all th...

Tinospora cordifolia (RTc) has already been reported to protect whole-body lethally irradiated mice. This study has focussed on certain aspects of immuno-competence, which are adversely affected by irradiation. This study included estimation of spleen size, cell count, DNA fragmentation and apoptosis in splenocytes. The adherence, spreading and phagocytic activities of macrophages were also ass...

The aim of the study was to evaluate anticancer activity methanol and aqueous extracts leaves Tinosporacordifolia Wild Miers against a Human Breast Carcinoma Cell line(MDAMB231) by MTT assay. coarse powder leaf were subjected Soxhletextraction microwave assisted extraction using water as solvent. IC50 values extract followed soxhlation found be 59.85μg/mL 249μg/mLrespectively in MDAMB231 cell...