background: the positive impacts of exercise therapy on patients’ cognitive problems still remain unknown. this study was a pilot intervention to examine the effects of combined exercise on the cognitive problems of patients with multiple sclerosis (ms) in iranian ms society over 2012 to 2013.   methods : this quasi-experimental research was carried out in the form of a pretest/posttest study. ...

Objective—To review and determine the eVectiveness of exercise treatment in osteoarthritis of the knee. Methods—A computerised literature search of Medline was carried out searching between June 1966 and January 2000. Results—Twenty three randomised controlled trials were identified from the literature. Only three trials were suYciently powered. Small to moderate beneficial eVects of exercise t...

The benefi ts of regular exercise to one’s physical health are widely known. Besides its benefi ts to physical health, exercise is also effective for improvements to both mental health and quality of life [Takenaka, (1998, 1999)]. However, although those benefi ts are recognized, it is not easy to continue regular exercise practices. In Japan, it is less than 30% of the total population those w...

BACKGROUND Short term exercise interventions have been shown to be beneficial for breast cancer survivors soon after treatments but longer term adherence is needed. PURPOSE To examine the effects of a supervised exercise program on motivational variables in breast cancer survivors using Self-Determination Theory (SDT). METHOD Sixty breast cancer survivors were randomized in a cross-over des...

BACKGROUND Several nonpharmacological interventions, including exercise, are recommended in primary prevention of hypertension and other cardiovascular diseases in which the pathogenetic role of endothelial dysfunction has been suggested. We studied the effects of long-term aerobic exercise on endothelial function in patients with essential hypertension. METHODS AND RESULTS The forearm blood ...

The purpose of the present study was to determine in human skeletal muscle whether a single exercise bout and 7 days of consecutive endurance (cycling) training 1) increased insulin-stimulated Akt pSer(473) and 2) altered the abundance of the protein tyrosine phosphatases (PTPases), PTP1B and SHP2. In healthy, untrained men (n = 8; 24 +/- 1 yr), glucose infusion rate during a hyperinsulinemic e...

Physical inactivity and exercise training result in opposite adaptations of vascular structure. However, the molecular mechanisms behind these adaptations are not completely understood. We used a unique study design to examine both vascular characteristics of the superficial femoral artery (using ultrasound) and gene expression levels (from a muscle biopsy) in human models for physical decondit...

Background. Although people with Multiple Sclerosis (pwMS) benefit from physical exercise, they still show reduced physical activity and exercise behaviour. This study aimed to investigate short- and long-term effects of an exercise-based patient education programme (ePEP) that focuses on empowering pwMS to a sustainable and self-regulated exercise training management. Methods. Fourteen pwMS we...

BACKGROUND Physical exercise during leisure time is known to increase physical capacity; however, the long-term effects on work ability and work strain are inconclusive. The aim of this study was to investigate the effects of a 6-month physical exercise program on work ability and work strain after 6 months and 30 months, among women with menopausal symptoms at baseline. METHODS A questionnai...

Maternal infection is an important factor causing neonatal brain injury and later developmental disability. In the present study, we investigated the effects of treadmill exercise intensity on short-term memory, hippocampal neurogenesis, and expression of brain-derived neurotrophic factor (BDNF), and tyrosine kinase receptor B (TrkB) in the rats born of lipopolysaccharide (LPS)-exposed maternal...