The aim of this study was to compare pentane-1,5-diol and propane-1,2-diol used as absorption enhancers for cutaneously administered terbinafine. Fresh human skin samples were placed in a continuous flow diffusion cell with a gel containing terbinafine on top of the skin. Receptor fluid samples were analysed using high - performance liquid chromatography. The quantity of gel remaining on the sk...

The antifungal activities of fluconazole, itraconazole, ketoconazole, terbinafine and griseofulvin were tested by broth microdilution technique, against 60 dermatophytes isolated from nail or skin specimens from Goiania city patients, Brazil. In this study, the microtiter plates were incubated at 28 masculineC allowing a reading of the minimal inhibitory concentration (MIC) after four days of i...

background and objectives: vaginal candidiasis is a common disease in women during their lifetime and occurs in diabetes patients, during pregnancy and oral contraceptives users. although several antifungals are routinely used for treatment; however, vaginal candidiasis is a challenge for patients and gynecologists. the aim of the present study was to evaluate terbinafine (lamisil) on candida v...

BACKGROUND Subacute cutaneous lupus erythematosus is a nonscarring, non-atrophy-producing photosensitive cutaneous disorder. Half of the patients have 4 or more of the criteria for classification as systemic lupus erythematosus. In some patients, drugs induce or exacerbate the cutaneous disease. OBSERVATION We describe 5 patients who had either an exacerbation or a new onset of subacute cutan...

These two brand names are too similar, while the international non-proprietary names (INNs) are clearly different: lamotrigine (an antiepileptic) and terbinafine (an antifungal drug).

Terbinafine is an allylamine antifungal agent, effective in the treatment of dermatomycoses. Many cutaneous adverse reactions have been reported (in about 3% of treated patients). Furthermore terbinafine has been associated with pustular eruptions, as well as the induction and exacerbation of pre-existing psoriasis and acute generalized exanthematous pustulosis (AGEP). AGEP is an uncommon asept...

Pogostemon cablin Benth's leaves, which belong to the Lamiaceae family, are used make patchouli essential oil (PEO). Sesquiterpenes main compounds in oil. Antibacterial, antifungal, antiviral, antiemetic, and anti-inflammatory activities just a few of many pharmacological actions that well-known. In this investigation, cefuroxime (CEF), moxifloxacin (MOX), clarithromycin (CLA), fluconazole (FLU...

BACKGROUND The standard treatment of Trichophyton rubrum nail bed onychomycosis (or distal subungual onychomycosis [DSO]) with daily terbinafine for 12 weeks involves treating for a fixed period shorter than the time required for complete replacement of the nail bed and overlying nail plate by normal growth. The same total amount of terbinafine pulse-dosed for approximately 12 months would trea...